(Q44152741)

30 November 2017

title

Active-site clashes prevent the human 3-methyladenine DNA glycosylase from improperly removing bases (English)

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30 November 2017

Ellen E Connor

1

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30 November 2017

Michael D Wyatt

series ordinal

2

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30 November 2017

publication date

1 September 2002

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30 November 2017

published in

Chemistry and Biology

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30 November 2017

volume

9

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30 November 2017

issue

9

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30 November 2017

page(s)

1033-1041

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Genome maintenance mechanisms for preventing cancer

30 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Quality control by DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Human DNA repair genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Recent progress in the biology, chemistry and structural biology of DNA glycosylases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Initiation of base excision repair: glycosylase mechanisms and structures

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Envisioning the molecular choreography of DNA base excision repair

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

3-methyladenine DNA glycosylases: structure, function, and biological importance

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

What structural features determine repair enzyme specificity and mechanism in chemically modified DNA?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Escherichia coli, Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N6-ethenoadenine when present in DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

1,N6-ethenoadenine is preferred over 3-methyladenine as substrate by a cloned human N-methylpurine-DNA glycosylase (3-methyladenine-DNA glycosylase)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Substrate specificity of human methylpurine DNA N-glycosylase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Purification and characterization of human 3-methyladenine-DNA glycosylase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

1,N(2)-ethenoguanine, a mutagenic DNA adduct, is a primary substrate of Escherichia coli mismatch-specific uracil-DNA glycosylase and human alkylpurine-DNA-N-glycosylase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Base excision and DNA binding activities of human alkyladenine DNA glycosylase are sensitive to the base paired with a lesion

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Interactions of the human, rat, Saccharomyces cerevisiae and Escherichia coli 3-methyladenine-DNA glycosylases with DNA containing dIMP residues

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Influence of DNA structure on hypoxanthine and 1,N(6)-ethenoadenine removal by murine 3-methyladenine DNA glycosylase.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Release of normal bases from intact DNA by a native DNA repair enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Generation of a strong mutator phenotype in yeast by imbalanced base excision repair

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Interaction of the recombinant human methylpurine-DNA glycosylase (MPG protein) with oligodeoxyribonucleotides containing either hypoxanthine or abasic sites

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Specific interaction of wild-type and truncated mouse N-methylpurine-DNA glycosylase with ethenoadenine-containing DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Specific binding of a designed pyrrolidine abasic site analog to multiple DNA glycosylases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Studies on the base pairing properties of deoxyinosine by solid phase hybridisation to oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Refined crystal structure of an octanucleotide duplex with I.T. mismatched base pairs

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Crystal structure of a B-DNA dodecamer containing inosine, d(CGCIAATTCGCG), at 2.4 A resolution and its comparison with other B-DNA dodecamers

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Regulation and expression of the adaptive response to alkylating agents

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Correlation between sequence-dependent glycosylase repair and the thermal stability of oligonucleotide duplexes containing 1, N6-ethenoadenine

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Base excision repair in a network of defence and tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Cisplatin adducts inhibit 1,N(6)-ethenoadenine repair by interacting with the human 3-methyladenine DNA glycosylase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Binding of specific DNA base-pair mismatches by N-methylpurine-DNA glycosylase and its implication in initial damage recognition

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Effects of hydrogen bonding within a damaged base pair on the activity of wild type and DNA-intercalating mutants of human alkyladenine DNA glycosylase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Transgenic systems in studies on genotoxicity of alkylating agents: critical lesions, thresholds and defense mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents--a case of imbalanced DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

Increased resistance of the Chinese hamster mutant irs1 cells to monofunctional alkylating agents by transfection of the E. coli or mammalian N3-methyladenine-DNA-glycosylase genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

3T3 NIH murine fibroblasts and B78 murine melanoma cells expressing the Escherichia coli N3-methyladenine-DNA glycosylase I do not become resistant to alkylating agents

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900215-6

7 January 2021

10.1016/S1074-5521(02)00215-6

Identifiers

DOI

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30 November 2017

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