(Q44173929)

English

Dual NK(1) antagonists--serotonin reuptake inhibitors as potential antidepressants. Part 2: SAR and activity of benzyloxyphenethyl piperazine derivatives

scientific article published in November 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Dual NK(1) antagonists--serotonin reuptake inhibitors as potential antidepressants. Part 2: SAR and activity of benzyloxyphenethyl piperazine derivatives (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

2

object named as

Olivier Berton

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

author name string

Thomas Ryckmans

1

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Renée Grimée

3

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Europe PubMed Central

PubMed publication ID

30 November 2017

Thierry Kogej

4

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Yves Lamberty

5

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Patrick Pasau

6

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Patrice Talaga

7

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Christophe Genicot

8

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

language of work or name

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publication date

1 November 2002

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Europe PubMed Central

PubMed publication ID

30 November 2017

number of pages

4

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inferred from page(s)

Bioorganic & Medicinal Chemistry Letters

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30 November 2017

12

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30 November 2017

21

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30 November 2017

3195-3198

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Europe PubMed Central

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30 November 2017

First dual NK(1) antagonists-serotonin reuptake inhibitors: synthesis and SAR of a new class of potential antidepressants

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Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists.

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Estrogen actions in the central nervous system

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Toward selective ERbeta agonists for central nervous system disorders: synthesis and characterization of aryl benzthiophenes

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The role of corticotropin-releasing factor in depression and anxiety disorders.

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The CRF peptide family and their receptors: yet more partners discovered

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Corticotropin releasing factor (CRF) receptor modulators: progress and opportunities for new therapeutic agents

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Corticotropin-releasing hormone receptor antagonists: framework design and synthesis guided by ligand conformational studies

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Distinct mechanism for antidepressant activity by blockade of central substance P receptors

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Update on Substance P (NK-1 receptor) antagonists in clinical trials for depression

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Novel strategies for pharmacotherapy of depression

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The NK1-receptor antagonist NKP608 has an antidepressant-like effect in the chronic mild stress model of depression in rats

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Synthesis and structure-activity relationships of CP-122,721, a second-generation NK-1 receptor antagonist

1 reference

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Effect of neurokinin-I receptor antagonists on the function of 5-HT and noradrenaline neurons

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Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function

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Design, synthesis and biological evaluation of new 3-[(4-aryl)piperazin-1-yl]-1-arylpropane derivatives as potential antidepressants with a dual mode of action: serotonin reuptake inhibition and 5-HT1A receptor antagonism

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5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization.

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Characterization of [3H]paroxetine binding in rat brain

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A new synthesis of α-arylglycines from aryl boronic acids

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Highly Stereocontrolled One-Step Synthesis ofanti-β-Amino Alcohols from Organoboronic Acids, Amines, and α-Hydroxy Aldehydes

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Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs

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Differential inhibition of foot tapping and chromodacryorrhoea in gerbils by CNS penetrant and non-penetrant tachykinin NK1 receptor antagonists

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Pharmacological blockade or genetic deletion of substance P (NK(1)) receptors attenuates neonatal vocalisation in guinea-pigs and mice.

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Identifiers

10.1016/S0960-894X(02)00563-2

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

release_7si2vtqqxjfxjop4fmoiwwvirq

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https://api.fatcat.wiki/v0/release/7si2vtqqxjfxjop4fmoiwwvirq

24 November 2022

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mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

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