(Q44193646)

30 November 2017

title

Correlation between troglitazone cytotoxicity and drug metabolic enzyme activities in cryopreserved human hepatocytes (English)

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30 November 2017

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8

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30 November 2017

Ryan Butler

4

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author name string

Nicola J Hewitt

1

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30 November 2017

Scott Lloyd

2

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30 November 2017

Mike Hayden

3

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30 November 2017

Yumiko Sakai

5

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30 November 2017

Ryan Springer

6

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30 November 2017

Andrew Fackett

7

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30 November 2017

language of work or name

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1 November 2002

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Chemico-biological Interactions

30 November 2017

published in

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30 November 2017

volume

142

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30 November 2017

issue

1-2

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30 November 2017

page(s)

73-82

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Two cases of severe clinical and histologic hepatotoxicity associated with troglitazone

30 November 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900055-8

Troglitazone-induced hepatic failure leading to liver transplantation. A case report

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900055-8

An autopsy case of troglitazone-induced fulminant hepatitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900055-8

Severe hepatotoxicity associated with troglitazone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900055-8

Clinical pharmacokinetics of troglitazone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900055-8

Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900055-8

Pharmacokinetics of troglitazone, a PPAR-gamma agonist, in patients with hepatic insufficiency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900055-8

Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900055-8

Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900055-8

Present status of the application of cryopreserved hepatocytes in the evaluation of xenobiotics: consensus of an international expert panel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900055-8

Optimization of cryopreservation procedures for rat and human hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900055-8

10.1016/S0009-2797(02)00055-8

7 January 2021

Identifiers

DOI

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30 November 2017

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