(Q44194392)

30 November 2017

Genomic studies of the spleen protein tyrosine kinase locus reveal a complex promoter structure and several genetic variants (English)

1 reference

30 November 2017

4

Fatih Uckun

1 reference

30 November 2017

Patricia A Goodman

1

1 reference

PubMed ID

12400606

30 November 2017

Brian Jurana

series ordinal

2

1 reference

PubMed ID

12400606

30 November 2017

Carla M Wood

series ordinal

3

1 reference

30 November 2017

1 August 2002

1 reference

30 November 2017

1 reference

30 November 2017

43

1 reference

30 November 2017

8

1 reference

30 November 2017

1627-1635

1 reference

Syk is required for BCR-mediated activation of p90Rsk, but not p70S6k, via a mitogen-activated protein kinase-independent pathway in B cells

30 November 2017

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Protein tyrosine kinases in the initiation of antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Leukocyte protein tyrosine kinases: potential targets for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Regulation of antigen receptor signal transduction by protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

A deficiency in Syk enhances ceramide-induced apoptosis in DT40 lymphoma B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Human spleen tyrosine kinase p72Syk associates with the Src-family kinase p53/56Lyn and a 120-kDa phosphoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Syk tyrosine kinase required for mouse viability and B-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Protein-tyrosine kinase Syk expressed in human nasal fibroblasts and its effect on RANTES production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Syk protein-tyrosine kinase is involved in neuron-like differentiation of embryonal carcinoma P19 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Antibodies directed against ZAP-70 cross-react with a 66 kDa tyrosine kinase in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Spleen tyrosine kinase (Syk) deficiency in childhood pro-B cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Constitutive kinase activation of the TEL-Syk fusion gene in myelodysplastic syndrome with t(9;12)(q22;p12).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Initial sequencing and analysis of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Cloning of the cDNA for the deleted syk kinase homologous to ZAP-70 from human basophilic leukemia cell line (KU812).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Molecular cloning of the human homologue to the pig protein-tyrosine kinase syk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Genetic polymorphism of human interleukin-1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

An intronic polymorphic repeat sequence modulates interleukin-1 alpha gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Apolipoprotein E gene promoter polymorphisms in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Regulation of the mammalian alcohol dehydrogenase genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Function of the C-36 to T polymorphism in the human cholecystokinin gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Natural variation in immune responsiveness, with special reference to immunodeficiency and promoter polymorphism in class II MHC genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Genetic polymorphisms in the renin-angiotensin system: relevance for susceptibility to cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Dissection of differentially regulated (G+C)-rich promoters of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

The structural and functional diversity of dystrophin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Differentially expressed messenger RNA isoforms of the human estrogen receptor-alpha gene are generated by alternative splicing and promoter usage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

The multiple untranslated first exons and promoters system of the oestrogen receptor gene in the brain and peripheral tissues of the rat and monkey and the developing rat cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Evidence for a previously unidentified upstream exon in the human oestrogen receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

Identification of two estrogen receptor transcripts with novel 5' exons isolated from a MCF7 cDNA library

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

An analysis of vertebrate mRNA sequences: intimations of translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819021000002965

10.1080/1042819021000002965

21 January 2018

Identifiers

DOI

1 reference

30 November 2017

1 reference

PubMed ID

12400606