(Q44223718)

English

Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex

scientific article published in December 2002

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scholarly article

1 reference

Europe PubMed Central

1 December 2017

Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex (English)

1 reference

Europe PubMed Central

1 December 2017

0 references

endoplasmic reticulum

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immunosuppression

1 reference

based on heuristic

inferred from title

author name string

Phillis JW

1

1 reference

Europe PubMed Central

1 December 2017

Diaz FG

2

1 reference

Europe PubMed Central

1 December 2017

O'Regan MH

3

1 reference

Europe PubMed Central

1 December 2017

Pilitsis JG

4

1 reference

Europe PubMed Central

1 December 2017

language of work or name

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publication date

1 December 2002

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Europe PubMed Central

1 December 2017

number of pages

13

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based on heuristic

inferred from page(s)

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Europe PubMed Central

1 December 2017

957

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Europe PubMed Central

1 December 2017

12-24

1 reference

Europe PubMed Central

1 December 2017

1

1 reference

Europe PubMed Central

1 December 2017

In vivo prevention of adriamycin cardiotoxicity by cyclosporin A or FK506

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Calcineurin and mitochondrial function in glutamate-induced neuronal cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

s-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Mitochondria recycle Ca(2+) to the endoplasmic reticulum and prevent the depletion of neighboring endoplasmic reticulum regions

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Reversible inhibition of calcineurin by the polyphenolic aldehyde gossypol.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Cyclosporin A-sensitive and insensitive mechanisms produce the permeability transition in mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Ryanodine sensitizes the cardiac Ca(2+) release channel (ryanodine receptor isoform 2) to Ca(2+) activation and dissociates as the channel is closed by Ca(2+) depletion

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

The phospholipase A2 inhibitor, quinacrine, reduces infarct size in rats after transient middle cerebral artery occlusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Intracellular calcium signals regulating cytosolic phospholipase A2 translocation to internal membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases

1 reference

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7 January 2021

Dantrolene Prevents Glutamate Cytotoxicity and Ca2+Release from Intracellular Stores in Cultured Cerebral Cortical Neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Immunophilins in protein folding and immunosuppression.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Xestospongins: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Release and sequestration of calcium by ryanodine-sensitive stores in rat hippocampal neurones

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

The effects of dantrolene alone or in combination with nimodipine in glutamate-induced neurotoxicity in cerebellar granular cell cultures of rat pups

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Immunophilins: beyond immunosuppression

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Trifluoperazine and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurones

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

An immunosuppressant, FK506, protects hippocampal neurons from forebrain ischemia in the mongolian gerbil.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

ATP stimulates calcium-dependent glutamate release from cultured astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

The calmodulin antagonist trifluoperazine in transient focal brain ischemia in rats. Anti-ischemic effect and therapeutic window

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Chromaffin-cell stimulation triggers fast millimolar mitochondrial Ca2+ transients that modulate secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Potential role of calcineurin for brain ischemia and traumatic injury

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Mitochondria and neuronal survival

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Ca2+ marks: miniature calcium signals in single mitochondria driven by ryanodine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Disturbances of the functioning of endoplasmic reticulum: a key mechanism underlying neuronal cell injury?

1 reference

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7 January 2021

Cerebroprotective action of the phospholipase inhibitor quinacrine in the ischemia/reperfused gerbil hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Mechanisms of glutamate and aspartate release in the ischemic rat cerebral cortex.

1 reference

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7 January 2021

Inhibition of mitochondrial Na(+)/Ca(2+) exchange by 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one attenuates free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury

1 reference

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7 January 2021

Differential effects of phospholipase inhibitors on free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Structural proximity of mitochondria to calcium release units in rat ventricular myocardium may suggest a role in Ca2+ sequestration

1 reference

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7 January 2021

Identification of simian cyclophilin A as a calreticulin-binding protein in yeast two-hybrid screen and demonstration of cyclophilin A interaction with calreticulin

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Characterization of phospholipase A2 (PLA2) activity in gerbil brain: enhanced activities of cytosolic, mitochondrial, and microsomal forms after ischemia and reperfusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Activation of cPLA2, PKC, and ERKs in the rat cerebral cortex during ischemia/reperfusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Cyclosporin A inhibits inositol 1,4,5-trisphosphate-dependent Ca2+ signals by enhancing Ca2+ uptake into the endoplasmic reticulum and mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Immunophilins in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Calmodulin in ischemic neurotoxicity of rat hippocampus in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Neuroprotective effect of FK506, an immunosuppressant, on transient global ischemia in gerbil.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Calreticulin modulates capacitative Ca2+ influx by controlling the extent of inositol 1,4,5-trisphosphate-induced Ca2+ store depletion.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Effect of immunosuppressant FK506 on ischemia-induced degeneration of hippocampal neurons in gerbils

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Cytosolic Ca2+ changes during in vitro ischemia in rat hippocampal slices: major roles for glutamate and Na+-dependent Ca2+ release from mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903578-3

7 January 2021

Phenothiazines reduce ischemic damage to the central nervous system

1 reference

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7 January 2021

Identifiers

10.1016/S0006-8993(02)03578-3

1 reference

Europe PubMed Central

1 December 2017

1 reference

Europe PubMed Central

1 December 2017

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