(Q44226360)

1 December 2017

title

The final cut: how ERAP1 trims MHC ligands to size (English)

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1 December 2017

2

Olaf Rötzschke

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1 December 2017

Kirsten Falk

1

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1 December 2017

language of work or name

English

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publication date

1 December 2002

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1 December 2017

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1 December 2017

volume

3

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1 December 2017

issue

12

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1 December 2017

page(s)

1121-1122

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An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

1 December 2017

cites work

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https://api.crossref.org/works/10.1038%2FNI1202-1121

The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

21 January 2018

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https://api.crossref.org/works/10.1038%2FNI1202-1121

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1202-1121

Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1202-1121

Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1202-1121

Two new proteases in the MHC class I processing pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1202-1121

Cellular responses to interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1202-1121

Cellular peptide composition governed by major histocompatibility complex class I molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1202-1121

Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1202-1121

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1202-1121

MHC class I molecules can direct proteolytic cleavage of antigenic precursors in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1202-1121

The nature of the MHC class I peptide loading complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1202-1121

Proteasome inhibitors as new anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1202-1121

21 January 2018

Identifiers

DOI

10.1038/NI1202-1121

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1 December 2017

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