(Q44226726)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606059%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Comparative pharmaceutical metabolism by rainbow trout (Oncorhynchus mykiss) liver S9 fractions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606059%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

0 references

1

1 reference

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29 February 2020

Bryan W. Brooks

7

1 reference

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29 February 2020

Kevin Chambliss

5

1 reference

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29 February 2020

author name string

Bowen Du

2

1 reference

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29 February 2020

Patrick N Fitzsimmons

3

1 reference

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29 February 2020

Alex D Hoffman

4

1 reference

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29 February 2020

John W Nichols

6

1 reference

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29 February 2020

publication date

21 June 2013

1 reference

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Environmental Toxicology and Chemistry

29 February 2020

published in

1 reference

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29 February 2020

volume

32

1 reference

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29 February 2020

issue

8

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29 February 2020

page(s)

1810-1818

1 reference

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Occurrence and fate of human pharmaceuticals in the environment

29 February 2020

cites work

1 reference

Effluent from drug manufactures contains extremely high levels of pharmaceuticals.

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1 reference

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Leveraging mammalian pharmaceutical toxicology and pharmacology data to predict chronic fish responses to pharmaceuticals

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Liver microsomes and S9 from rainbow trout (Oncorhynchus mykiss): comparison of basal-level enzyme activities with rat and determination of xenobiotic intrinsic clearance in support of bioaccumulation assessment

21 January 2018

1 reference

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21 January 2018

1 reference

Cryopreserved hepatocytes from rainbow trout (Oncorhynchus mykiss): a validation study to support their application in bioaccumulation assessment

21 January 2018

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The influence of gill and liver metabolism on the predicted bioconcentration of three pharmaceuticals in fish

21 January 2018

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Cross-species comparison of fluoxetine metabolism with fish liver microsomes

21 January 2018

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Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Immunochemical relationships of cytochrome P4503A-like proteins in teleost fish

21 January 2018

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Comparison of basal level metabolic enzyme activities of freshly isolated hepatocytes from rainbow trout (Oncorhynchus mykiss) and rat.

21 January 2018

1 reference

Assessment of cytochrome P450 fluorometric substrates with rainbow trout and killifish exposed to dexamethasone, pregnenolone-16alpha-carbonitrile, rifampicin, and beta-naphthoflavone

21 January 2018

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Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae.

21 January 2018

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Comparison of P450s from human and fugu: 420 million years of vertebrate P450 evolution

21 January 2018

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Kinetics of hepatic phase I and II biotransformation reactions in eight finfish species.

21 January 2018

1 reference

Uptake and biological effects of environmentally relevant concentrations of the nonsteroidal anti-inflammatory pharmaceutical diclofenac in rainbow trout (Oncorhynchus mykiss).

21 January 2018

1 reference

Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data

21 January 2018

1 reference

Analysis of paroxetine, fluoxetine and norfluoxetine in fish tissues using pressurized liquid extraction, mixed mode solid phase extraction cleanup and liquid chromatography-tandem mass spectrometry

21 January 2018

1 reference

Therapeutic levels of levonorgestrel detected in blood plasma of fish: results from screening rainbow trout exposed to treated sewage effluents

21 January 2018

1 reference

Occurrence of pharmaceuticals and personal care products in German fish tissue: a national study.

21 January 2018

1 reference

Toxic effects of the non-steroidal anti-inflammatory drug diclofenac. Part I: histopathological alterations and bioaccumulation in rainbow trout

21 January 2018

1 reference

Variations in bioconcentration of human pharmaceuticals from sewage effluents into fish blood plasma.

21 January 2018

1 reference

Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation.

21 January 2018

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Evaluation of fresh and cryopreserved hepatocytes as in vitro drug metabolism tools for the prediction of metabolic clearance

21 January 2018

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Use of intrinsic clearance for prediction of human hepatic clearance

21 January 2018

1 reference

Evaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds.

21 January 2018

1 reference

Can in vitro metabolism-dependent covalent binding data distinguish hepatotoxic from nonhepatotoxic drugs? An analysis using human hepatocytes and liver S-9 fraction

21 January 2018

1 reference

Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose

21 January 2018

1 reference

Water quality of effluent-dominated ecosystems: ecotoxicological, hydrological, and management considerations

21 January 2018

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7 January 2021

Analysis of pharmaceuticals in fish using liquid chromatography-tandem mass spectrometry

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7 January 2021

Pharmaceuticals and personal care products: research needs for the next decade

1 reference

7 January 2021

Use ofIn VitroAbsorption, Distribution, Metabolism, and Excretion (ADME) Data in Bioaccumulation Assessments for Fish

1 reference

7 January 2021

Ibuprofen metabolism in the liver and gill of rainbow trout, Oncorhynchus mykiss

1 reference

7 January 2021

Drug-induced changes in P450 enzyme expression at the gene expression level: a new dimension to the analysis of drug-drug interactions

1 reference

7 January 2021

Radioactive assay for aryl hydrocarbon hydroxylase. Improved method and biological importance

1 reference

7 January 2021

Uptake from water, biotransformation, and biliary excretion of pharmaceuticals by rainbow trout

1 reference

7 January 2021

Toward an integrated human clearance prediction strategy that minimizes animal use

1 reference

7 January 2021