(Q44231100)

1 December 2017

title

The transmembrane domain of the amyloid precursor protein in microsomal membranes is on both sides shorter than predicted (English)

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1 December 2017

main subject

transmembrane protein

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author

Tobias Hartmann

series ordinal

5

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1 December 2017

4

Konrad Beyreuther

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1 December 2017

Stefan F Lichtenthaler

series ordinal

6

object named as

Stefan F Lichtenthaler

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1 December 2017

3

Colin L Masters

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1 December 2017

Beate Grziwa

1

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1 December 2017

Marcus O W Grimm

series ordinal

2

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1 December 2017

language of work or name

English

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publication date

25 November 2002

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Journal of Biological Chemistry

1 December 2017

published in

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1 December 2017

volume

278

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1 December 2017

issue

9

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1 December 2017

page(s)

6803-6808

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The Role of presenilins in gamma-secretase activity

1 December 2017

cites work

1 reference

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21 January 2018

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

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The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

21 January 2018

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The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

21 January 2018

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21 January 2018

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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

21 January 2018

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Nuclear access and action of notch in vivo

21 January 2018

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21 January 2018

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21 January 2018

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

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Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities

21 January 2018

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Production of the Alzheimer amyloid beta protein by normal proteolytic processing

21 January 2018

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Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

21 January 2018

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Beta-amyloid precursor protein. Location of transmembrane domain and specificity of gamma-secretase cleavage

21 January 2018

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Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein

21 January 2018

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The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain

21 January 2018

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Cleavage at the N-terminal site of Alzheimer amyloid beta/A4 protein is essential for its secretion.

21 January 2018

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An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 January 2018

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Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs

21 January 2018

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Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases

21 January 2018

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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

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Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?

21 January 2018

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Isolation of intracellular membranes by means of sodium carbonate treatment: application to endoplasmic reticulum

21 January 2018

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Key residues for membrane binding, oligomerization, and pore forming activity of staphylococcal alpha-hemolysin identified by cysteine scanning mutagenesis and targeted chemical modification.

21 January 2018

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Amyloidogenicity of rodent and human beta A4 sequences

21 January 2018

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

21 January 2018

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Localization of proteins to the Golgi apparatus

21 January 2018

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Cholesterol and the Golgi apparatus

21 January 2018

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Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

21 January 2018

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Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

21 January 2018

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Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains

21 January 2018

1 reference

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A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing

21 January 2018

1 reference

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Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch

21 January 2018

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A simple method for displaying the hydropathic character of a protein

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M210047200

1 reference

release_rcgu4wa7fncqnnhjvwyeemusxe

1 December 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rcgu4wa7fncqnnhjvwyeemusxe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference