(Q44277460)

English

Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression

scientific article published in February 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression (English)

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Europe PubMed Central

PubMed publication ID

1 December 2017

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Frederick R. Appelbaum

2

object named as

F R Appelbaum

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Europe PubMed Central

PubMed publication ID

1 December 2017

Cheryl L. Willman

3

object named as

C L Willman

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Europe PubMed Central

PubMed publication ID

1 December 2017

author name string

D L Stirewalt

1

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Europe PubMed Central

PubMed publication ID

1 December 2017

R A Zager

4

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Europe PubMed Central

PubMed publication ID

1 December 2017

D E Banker

5

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Europe PubMed Central

PubMed publication ID

1 December 2017

publication date

1 February 2003

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Europe PubMed Central

PubMed publication ID

1 December 2017

Leukemia Research

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Europe PubMed Central

PubMed publication ID

1 December 2017

27

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1 December 2017

2

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Europe PubMed Central

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1 December 2017

133-145

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Europe PubMed Central

PubMed publication ID

1 December 2017

Regulation of the mevalonate pathway

1 reference

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Cholesterol lowering in the management of coronary artery disease: the clinical implications of recent trials

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7 January 2021

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Suppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

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Lipid metabolism as a target for brain cancer therapy: synergistic activity of lovastatin and sodium phenylacetate against human glioma cells.

1 reference

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Inhibitory effect of simvastatin on the proliferation of human myeloid leukaemia cells in severe combined immunodeficient (SCID) mice

1 reference

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7 January 2021

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RAS and leukemia: from basic mechanisms to gene-directed therapy

1 reference

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Lovastatin and tumor necrosis factor-alpha exhibit potentiated antitumor effects against Ha-ras-transformed murine tumor via inhibition of tumor-induced angiogenesis

1 reference

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A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis

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Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells

1 reference

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Increased proximal tubular cholesterol content: implications for cell injury and "acquired cytoresistance"

1 reference

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7 January 2021

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Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

1 reference

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Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1 reference

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Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms

1 reference

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'Cold SSCP': a simple, rapid and non-radioactive method for optimized single-strand conformation polymorphism analyses

1 reference

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Interaction of cytosine arabinoside and lovastatin in human leukemia cells

1 reference

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Effect of simvastatin alone and in combination with cytosine arabinoside on the proliferation of myeloid leukemia cell lines

1 reference

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Ras regulatory interactions: novel targets for anti-cancer intervention?

1 reference

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Lovastatin induced control of blast cell growth in an elderly patient with acute myeloblastic leukemia

1 reference

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7 January 2021

based on heuristic

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The widening role of statins: RAS signal transduction and drug-induced cytotoxicity in human leukemia: a commentary to 'interaction of cytosine arabinoside and lovastatin in human leukemia cells'.

1 reference

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7 January 2021

based on heuristic

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Detection of high incidence of H-RAS oncogene point mutations in acute myelogenous leukemia

1 reference

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7 January 2021

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RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2802%2900085-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects

1 reference

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7 January 2021

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Analysis of the transforming potential of the human H-ras gene by random mutagenesis

1 reference

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7 January 2021

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The oncogenic activation of human p21ras by a novel mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2802%2900085-1

7 January 2021

based on heuristic

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FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia.

1 reference

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7 January 2021

based on heuristic

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Lack of constitutive activation of MAP kinase pathway in human acute myeloid leukemia cells with N-Ras mutation

1 reference

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7 January 2021

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Rapid and reliable detection of N-ras mutations in acute lymphoblastic leukemia by melting curve analysis using LightCycler technology

1 reference

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7 January 2021

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Lipid-dependent Targeting of G Proteins into Rafts

1 reference

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Expression of caveolin-1 in human T cell leukemia cell lines

1 reference

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7 January 2021

based on heuristic

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Identifiers

10.1016/S0145-2126(02)00085-1

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

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