(Q44292889)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12551927%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

title

Epoxycyclohexenone inhibits Fas-mediated apoptosis by blocking activation of pro-caspase-8 in the death-inducing signaling complex (English)

1 reference

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17 December 2019

2

1 reference

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17 December 2019

author name string

Yasunobu Miyake

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12551927%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

Takao Kataoka

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12551927%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

Hiroyuki Osada

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12551927%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

language of work or name

English

0 references

publication date

24 January 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12551927%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

17 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12551927%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

volume

278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12551927%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

page(s)

11213-11220

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12551927%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12551927%20AND%20SRC:MED&resulttype=core&format=json

Apoptosis by death factor

17 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Death receptors: signaling and modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

An induced proximity model for caspase-8 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Inhibition of death receptor signals by cellular FLIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

IAP family proteins--suppressors of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Involvement of oxidative stress in tumor cytotoxic activity of hepatocyte growth factor/scatter factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Molecular ordering of the initial signaling events of CD95.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Signal transduction by tumor necrosis factor and its relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

A novel adenine nucleotide translocase inhibitor, MT-21, induces cytochrome c release by a mitochondrial permeability transition-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Autoproteolytic activation of pro-caspases by oligomerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Inhibition of human caspases by peptide-based and macromolecular inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Neuroprotection by a caspase inhibitor in acute bacterial meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Caspase inhibition reduces apoptosis and increases survival of nigral transplants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Inhibition of fas death signals by FLIPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

Actin cytoskeleton is required for early apoptosis signaling induced by anti-Fas antibody but not Fas ligand in murine B lymphoma A20 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

A new inhibitor of protein kinase C, RK-286C (4'-demethylamino-4'-hydroxystaurosporine). I. Screening, taxonomy, fermentation and biological activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209610200

21 January 2018

Identifiers

DOI

10.1074/JBC.M209610200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12551927%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

1 reference