(Q44297110)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29023421%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

review article

3 references

PubMed publication ID

5 July 2022

29 July 2022

Helicobacter pylori Vacuolating Toxin and Gastric Cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29023421%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

1 reference

2 November 2019

3 references

20 November 2019

5 July 2022

29 July 2022

1 reference

20 November 2019

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29023421%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

author name string

Mark S McClain

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29023421%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

Amber C Beckett

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29023421%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

language of work or name

1 reference

12 October 2017

7 references

21 March 2019

3 April 2019

2 November 2019

20 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29023421%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

5 July 2022

29 July 2022

7 references

21 March 2019

3 April 2019

2 November 2019

20 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29023421%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

5 July 2022

29 July 2022

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29023421%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29023421%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

7 April 2020

copyright license

6 references

21 March 2019

3 April 2019

2 November 2019

20 November 2019

5 July 2022

29 July 2022

0 references

on focus list of Wikimedia project

ScienceSource

0 references

cites work

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25 May 2018

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VacA's Induction of VacA-Containing Vacuoles (VCVs) and Their Immunomodulatory Activities on Human T Cells

25 May 2018

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The Immunomodulator VacA Promotes Immune Tolerance and Persistent Helicobacter pylori Infection through Its Activities on T-Cells and Antigen-Presenting Cells

25 May 2018

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25 May 2018

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Relationship between vacA Types and Development of Gastroduodenal Diseases

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25 May 2018

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New Insights into VacA Intoxication Mediated through Its Cell Surface Receptors

25 May 2018

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Helicobacter pylori Diversity and Gastric Cancer Risk

25 May 2018

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Molecular and Structural Analysis of the Helicobacter pylori cag Type IV Secretion System Core Complex.

25 May 2018

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Helicobacter pylori outer membrane protein Q allele distribution is associated with distinct pathologies in Pakistan.

25 May 2018

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Helicobacter pylori adaptation in vivo in response to a high-salt diet

25 May 2018

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Growth phase-dependent composition of the Helicobacter pylori exoproteome.

25 May 2018

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Characterization of Helicobacter pylori VacA-containing vacuoles (VCVs), VacA intracellular trafficking and interference with calcium signalling in T lymphocytes

25 May 2018

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Helicobacter pylori Activates and Expands Lgr5(+) Stem Cells Through Direct Colonization of the Gastric Glands

25 May 2018

1 reference

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Clinical relevance of Helicobacter pylori vacA and cagA genotypes in gastric carcinoma

25 May 2018

1 reference

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Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10.

25 May 2018

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Vacuolating cytotoxin genotypes are strong markers of gastric cancer and duodenal ulcer-associated Helicobacter pylori strains: a matched case-control study

25 May 2018

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Analysis of surface-exposed outer membrane proteins in Helicobacter pylori.

25 May 2018

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Helicobacter pylori CagA and gastric cancer: a paradigm for hit-and-run carcinogenesis

25 May 2018

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A role for the vacuolating cytotoxin, VacA, in colonization and Helicobacter pylori-induced metaplasia in the stomach.

25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis

25 May 2018

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Helicobacter pylori γ-glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence and immune tolerance

25 May 2018

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Polymorphism in the Helicobacter pylori CagA and VacA toxins and disease

25 May 2018

1 reference

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Reactive oxygen species-induced autophagic degradation of Helicobacter pylori CagA is specifically suppressed in cancer stem-like cells

25 May 2018

1 reference

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Structural analysis of the oligomeric states of Helicobacter pylori VacA toxin

25 May 2018

1 reference

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A novel method for genotyping the Helicobacter pylori vacA intermediate region directly in gastric biopsy specimens

25 May 2018

1 reference

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Remodeling the host environment: modulation of the gastric epithelium by the Helicobacter pylori vacuolating toxin (VacA).

25 May 2018

1 reference

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Low-density lipoprotein receptor-related protein-1 (LRP1) mediates autophagy and apoptosis caused by Helicobacter pylori VacA

25 May 2018

1 reference

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The intermediate region of Helicobacter pylori VacA is a determinant of toxin potency in a Jurkat T cell assay

25 May 2018

1 reference

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Intoxication strategy of Helicobacter pylori VacA toxin

25 May 2018

1 reference

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Helicobacter pylori vacuolating cytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death

25 May 2018

1 reference

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Helicobacter pylori homB, but not cagA, is associated with gastric cancer in Iran

25 May 2018

1 reference

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Helicobacter pylori perturbs iron trafficking in the epithelium to grow on the cell surface

25 May 2018

1 reference

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Helicobacter pylori VacA induces programmed necrosis in gastric epithelial cells.

25 May 2018

1 reference

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Architecture of the Helicobacter pylori Cag-type IV secretion system

25 May 2018

1 reference

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Assembly and molecular mode of action of the Helicobacter pylori Cag type IV secretion apparatus

25 May 2018

1 reference

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Helicobacter pylori VacA Reduces the Cellular Expression of STAT3 and Pro-survival Bcl-2 Family Proteins, Bcl-2 and Bcl-XL, Leading to Apoptosis in Gastric Epithelial Cells

25 May 2018

1 reference

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Molecular evolution of the Helicobacter pylori vacuolating toxin gene vacA

25 May 2018

1 reference

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Helicobacter pylori CagA inhibits endocytosis of cytotoxin VacA in host cells

25 May 2018

1 reference

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Sphingomyelin is important for the cellular entry and intracellular localization of Helicobacter pylori VacA.

25 May 2018

1 reference

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Reconstitution of Helicobacter pylori VacA toxin from purified components

25 May 2018

1 reference

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Endosome-mitochondria juxtaposition during apoptosis induced by H. pylori VacA

25 May 2018

1 reference

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Diversity of VacA intermediate region among Helicobacter pylori strains from several regions of the world.

25 May 2018

1 reference

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Epidemiological link between gastric disease and polymorphisms in VacA and CagA.

25 May 2018

1 reference

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Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Role of deletion located between the intermediate and middle regions of the Helicobacter pylori vacA gene in cases of gastroduodenal diseases

25 May 2018

1 reference

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homB status of Helicobacter pylori as a novel marker to distinguish gastric cancer from duodenal ulcer

25 May 2018

1 reference

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Outer membrane protein expression profile in Helicobacter pylori clinical isolates.

25 May 2018

1 reference

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Genome sequence analysis of Helicobacter pylori strains associated with gastric ulceration and gastric cancer

25 May 2018

1 reference

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Evaluation of the clinical significance of homB, a novel candidate marker of Helicobacter pylori strains associated with peptic ulcer disease

25 May 2018

1 reference

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Helicobacter pylori VacA disrupts apical membrane-cytoskeletal interactions in gastric parietal cells

25 May 2018

1 reference

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Sphingomyelin functions as a novel receptor for Helicobacter pylori VacA.

25 May 2018

1 reference

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Functional association between the Helicobacter pylori virulence factors VacA and CagA.

25 May 2018

1 reference

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Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin

25 May 2018

1 reference

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Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain

25 May 2018

1 reference

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Early endosomes associated with dynamic F-actin structures are required for late trafficking of H. pylori VacA toxin

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Resistance of primary murine CD4+ T cells to Helicobacter pylori vacuolating cytotoxin

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori HopH (OipA) and bacterial pathogenicity: genetic and functional genomic analysis of hopH gene polymorphisms

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Multiple chromosomal loci for the babA gene in Helicobacter pylori

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

The cell-specific phenotype of the polymorphic vacA midregion is independent of the appearance of the cell surface receptor protein tyrosine phosphatase beta

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori outer membrane proteins and gastroduodenal disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Mimicry of a host anion channel by a Helicobacter pylori pore-forming toxin

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori VacA cytotoxin: a probe for a clathrin-independent and Cdc42-dependent pinocytic pathway routed to late endosomes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Functional antagonism between Helicobacter pylori CagA and vacuolating toxin VacA in control of the NFAT signaling pathway in gastric epithelial cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori VacA, a paradigm for toxin multifunctionality

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Targeting of Helicobacter pylori vacuolating toxin to lipid raft membrane domains analysed by atomic force microscopy

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori toxin VacA is transferred to host cells via a novel contact-dependent mechanism.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Immunosuppressive and proinflammatory activities of the VacA toxin of Helicobacter pylori

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Determinants of Non-toxicity in the Gastric Pathogen Helicobacter pylori

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori CagA containing ITAM-like sequences localized to lipid rafts negatively regulates VacA-induced signaling in vivo

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Two different families of hopQ alleles in Helicobacter pylori

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Relationship between Helicobacter pylori babA2 status with gastric epithelial cell turnover and premalignant gastric lesions.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Plasma membrane cholesterol modulates cellular vacuolation induced by the Helicobacter pylori vacuolating cytotoxin

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Multiple oligomeric states of the Helicobacter pylori vacuolating toxin demonstrated by cryo-electron microscopy

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

How the loop and middle regions influence the properties of Helicobacter pylori VacA channels

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

A 12-amino-acid segment, present in type s2 but not type s1 Helicobacter pylori VacA proteins, abolishes cytotoxin activity and alters membrane channel formation

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Outer membrane targeting of passenger proteins by the vacuolating cytotoxin autotransporter of Helicobacter pylori

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Two distinctive cell binding patterns by vacuolating toxin fused with glutathione S-transferase: one high-affinity m1-specific binding and the other lower-affinity binding for variant m forms

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Vacuolating cytotoxin of Helicobacter pylori induces apoptosis in the human gastric epithelial cell line AGS.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Vacuolating cytotoxin of Helicobacter pylori plays a role during colonization in a mouse model of infection

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori genotypes may determine gastric histopathology

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Carboxy-terminal proteolytic processing of Helicobacter pylori vacuolating toxin.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Virulence factors of Helicobacter pylori responsible for gastric diseases in Mongolian gerbil

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Cell specificity of Helicobacter pylori cytotoxin is determined by a short region in the polymorphic midregion

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Natural diversity in the N terminus of the mature vacuolating cytotoxin of Helicobacter pylori determines cytotoxin activity.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Vacuolating cytotoxin (vacA) alleles of Helicobacter pylori comprise two geographically widespread types, m1 and m2, and have evolved through limited recombination.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

VacA from Helicobacter pylori: a hexameric chloride channel

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Allelic diversity of the Helicobacter pylori vacuolating cytotoxin gene in South Africa: rarity of the vacA s1a genotype and natural occurrence of an s2/m1 allele

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori vacuolating toxin forms anion-selective channels in planar lipid bilayers: possible implications for the mechanism of cellular vacuolation.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Identification of the Helicobacter pylori VacA toxin domain active in the cell cytosol

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Full-length sequence analysis of the vacA gene from cytotoxic and noncytotoxic Helicobacter pylori

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Experimental infection of Mongolian gerbils with wild-type and mutant Helicobacter pylori strains.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Prevalence of vacuolating cytotoxin production and distribution of distinct vacA alleles in Helicobacter pylori from China

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Heterogeneity in levels of vacuolating cytotoxin gene (vacA) transcription among Helicobacter pylori strains

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Selective inhibition of Ii-dependent antigen presentation by Helicobacter pylori toxin VacA.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals its pattern of assembly

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Role of vacuolating cytotoxin in gastritis due to Helicobacter pylori in gnotobiotic piglets

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Effects of Helicobacter pylori vacuolating cytotoxin on primary cultures of human gastric epithelial cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Binding and internalization of the Helicobacter pylori vacuolating cytotoxin by epithelial cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori cytotoxin induces vacuolation of primary human mucosal epithelial cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Pathological significance and molecular characterization of the vacuolating toxin gene of Helicobacter pylori

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Cytotoxic activity in broth-culture filtrates of Campylobacter pylori

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Purification and characterization of the vacuolating toxin from Helicobacter pylori

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

The Mongolian Gerbil: A Robust Model of Helicobacter pylori-Induced Gastric Inflammation and Cancer.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori CagA and VacA genotypes and gastric phenotype: a meta-analysis

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Disease association with two Helicobacter pylori duplicate outer membrane protein genes, homB and homA.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Importance of EGF receptor, HER2/Neu and Erk1/2 kinase signalling for host cell elongation and scattering induced by the Helicobacter pylori CagA protein: antagonistic effects of the vacuolating cytotoxin VacA.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori cytotoxin-associated genotype and gastric precancerous lesions.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

The concerted action of the Helicobacter pylori cytotoxin VacA and of the v-ATPase proton pump induces swelling of isolated endosomes.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Functional properties of the p33 and p55 domains of the Helicobacter pylori vacuolating cytotoxin.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori vacuolating cytotoxin enters cells, localizes to the mitochondria, and induces mitochondrial membrane permeability changes correlated to toxin channel activity

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Cellular vacuolation and mitochondrial cytochrome c release are independent outcomes of Helicobacter pylori vacuolating cytotoxin activity that are each dependent on membrane channel formation

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Vacuolation induced by VacA toxin of Helicobacter pylori requires the intracellular accumulation of membrane permeant bases, Cl(-) and water

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Key importance of the Helicobacter pylori adherence factor blood group antigen binding adhesin during chronic gastric inflammation.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

The effect of Helicobacter pylori on gastric acid secretion by isolated parietal cells from a guinea pig. Association with production of vacuolating toxin by H. pylori

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666363

Interactions between p-33 and p-55 Domains of theHelicobacter pyloriVacuolating Cytotoxin (VacA)

15 August 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS9100316

Helicobacter pyloritoxin VacA induces vacuole formation by acting in the cell cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS9100316

Vacuolating cytotoxin purified fromHelicobacter pyloricauses mitochondrial damage in human gastric cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS9100316

Geographic distribution of vacA allelic types of Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS9100316

Cutting edge: VacA, a vacuolating cytotoxin of Helicobacter pylori, directly activates mast cells for migration and production of proinflammatory cytokines

21 January 2018

1 reference

12 December 2020

Acid activation of Helicobacter pylori vacuolating cytotoxin (VacA) results in toxin internalization by eukaryotic cells

1 reference

12 December 2020

Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach

1 reference

12 December 2020

Effect of helicobacter pylori vacuolating toxin on maturation and extracellular release of procathepsin D and on epidermal growth factor degradation

1 reference

12 December 2020

A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer

1 reference

12 December 2020

Identification of the minimal intracellular vacuolating domain of the Helicobacter pylori vacuolating toxin

1 reference

12 December 2020

A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation

1 reference

12 December 2020

Helicobacter pylori cagA and vacA Genotypes as Predictors of Progression of Gastric Preneoplastic Lesions: A Long-Term Follow-Up in a High-Risk Area in Spain

1 reference

12 December 2020

Helicobacter pylori vacuolating toxin accumulates within the endosomal-vacuolar compartment of cultured gastric cells and potentiates the vacuolating activity of ammonia

1 reference

12 December 2020

Distribution of vacA genotypes in Helicobacter pylori strains isolated from Brazilian adult patients with gastritis, duodenal ulcer or gastric carcinoma

1 reference

12 December 2020

Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori

1 reference

12 December 2020

Helicobacter pylori vacuolating cytotoxin inhibits activation-induced proliferation of human T and B lymphocyte subsets

1 reference

12 December 2020

Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin

1 reference

12 December 2020

The Helicobacter pylori vacA s1, m1 genotype and cagA is associated with gastric carcinoma in Germany

1 reference

12 December 2020

Identifiers

DOI

10.3390/TOXINS9100316

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29023421%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29023421%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

PubMed publication ID

29023421

1 reference