(Q35024882)

5 August 2017

Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms (English)

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5 August 2017

1

Eran Elinav

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5 August 2017

6

Richard A Flavell

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5 August 2017

3

Christoph A Thaiss

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5 August 2017

Roni Nowarski

2

1 reference

5 August 2017

Bo Hu

series ordinal

4

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5 August 2017

Chengcheng Jin

series ordinal

5

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5 August 2017

language of work or name

English

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publication date

1 November 2013

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5 August 2017

Nature Reviews Cancer

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5 August 2017

13

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5 August 2017

759-771

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5 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nrc3611

5 August 2017

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cites work

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31 March 2020

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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

31 March 2020

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31 March 2020

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Hallmarks of Cancer: The Next Generation

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Infections as a major preventable cause of human cancer

31 March 2020

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Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

31 March 2020

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Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis

31 March 2020

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The association of Streptococcus bovis/gallolyticus with colorectal tumors: the nature and the underlying mechanisms of its etiological role

31 March 2020

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Intestinal inflammation targets cancer-inducing activity of the microbiota.

31 March 2020

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A module of negative feedback regulators defines growth factor signaling

31 March 2020

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Derailed endocytosis: an emerging feature of cancer

31 March 2020

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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.

31 March 2020

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Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

31 March 2020

1 reference

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

31 March 2020

1 reference

Spatial regulation of receptor tyrosine kinases in development and cancer

31 March 2020

1 reference

Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.

31 March 2020

1 reference

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

31 March 2020

1 reference

gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.

31 March 2020

1 reference

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

31 March 2020

1 reference

Helicobacter pylori cytotoxin-associated gene A activates the signal transducer and activator of transcription 3 pathway in vitro and in vivo

31 March 2020

1 reference

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

31 March 2020

1 reference

Interleukin-6--a key regulator of colorectal cancer development.

31 March 2020

1 reference

STATs in cancer inflammation and immunity: a leading role for STAT3

31 March 2020

1 reference

Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer.

31 March 2020

1 reference

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

31 March 2020

1 reference

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

31 March 2020

1 reference

Immunity, Inflammation, and Cancer

31 March 2020

1 reference

NF-kappaB: linking inflammation and immunity to cancer development and progression

31 March 2020

1 reference

Inflammation meets cancer, with NF-κB as the matchmaker

31 March 2020

1 reference

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

31 March 2020

1 reference

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

31 March 2020

1 reference

IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis

31 March 2020

1 reference

Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages

31 March 2020

1 reference

STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation.

31 March 2020

1 reference

Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

31 March 2020

1 reference

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22.

31 March 2020

1 reference

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

31 March 2020

1 reference

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

31 March 2020

1 reference

Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3

31 March 2020

1 reference

In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression

31 March 2020

1 reference

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

31 March 2020

1 reference

ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation

31 March 2020

1 reference

The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors

31 March 2020

1 reference

Stat3 activation in urothelial stem cells leads to direct progression to invasive bladder cancer

31 March 2020

1 reference

Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

31 March 2020

1 reference

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

31 March 2020

1 reference

Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia.

31 March 2020

1 reference

Cellular senescence: when bad things happen to good cells

31 March 2020

1 reference

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

31 March 2020

1 reference

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

31 March 2020

1 reference

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

31 March 2020

1 reference

T-helper-1-cell cytokines drive cancer into senescence

31 March 2020

1 reference

A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism

31 March 2020

1 reference

Cancer-related inflammation

31 March 2020

1 reference

Activated neutrophils induce an hMSH2-dependent G2/M checkpoint arrest and replication errors at a (CA)13-repeat in colon epithelial cells.

31 March 2020

1 reference

The role of DNA breaks in genomic instability and tumorigenesis

31 March 2020

1 reference

A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.

31 March 2020

1 reference

Role of AID in tumorigenesis

31 March 2020

1 reference

Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers

31 March 2020

1 reference

Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma

31 March 2020

1 reference

31 March 2020

1 reference

Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways

31 March 2020

1 reference

Cyclooxygenase-2 expression induces genomic instability in MCF10A breast epithelial cells

31 March 2020

1 reference

Methylation of polycomb target genes in intestinal cancer is mediated by inflammation

31 March 2020

1 reference

Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation

31 March 2020

1 reference

AACR centennial series: the biology of cancer metastasis: historical perspective

31 March 2020

1 reference

The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts.

31 March 2020

1 reference

Macrophage diversity enhances tumor progression and metastasis

31 March 2020

1 reference

The basics of epithelial-mesenchymal transition

31 March 2020

1 reference

Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids

31 March 2020

1 reference

Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells.

31 March 2020

1 reference

Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion

31 March 2020

1 reference

IL-1 is required for tumor invasiveness and angiogenesis

31 March 2020

1 reference

Inflammation and oncogenesis: a vicious connection

31 March 2020

1 reference

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

31 March 2020

1 reference

CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages

31 March 2020

1 reference

SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion

31 March 2020

1 reference

The role of myeloid cells in the promotion of tumour angiogenesis

31 March 2020

1 reference

Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice

31 March 2020

1 reference

Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors

31 March 2020

1 reference

Intracellular signals and events activated by cytokines of the tumor necrosis factor superfamily: From simple paradigms to complex mechanisms.

31 March 2020

1 reference

Metastasis: from dissemination to organ-specific colonization

31 March 2020

1 reference

Systemic inflammation increases cancer cell adhesion to hepatic sinusoids by neutrophil mediated mechanisms

31 March 2020

1 reference

CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3

31 March 2020

1 reference

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

31 March 2020

1 reference

Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway

31 March 2020

1 reference

Deciphering and reversing tumor immune suppression.

31 March 2020

1 reference

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

31 March 2020

1 reference

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

31 March 2020

1 reference

Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity

31 March 2020

1 reference

Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer.

31 March 2020

1 reference

Myeloid-derived suppressor cells as regulators of the immune system

31 March 2020

1 reference

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

31 March 2020

1 reference

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells.

31 March 2020

1 reference

T-regulatory cells: key players in tumor immune escape and angiogenesis

31 March 2020

1 reference

A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells.

31 March 2020

1 reference

Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells

31 March 2020

1 reference

Why do viruses cause cancer? Highlights of the first century of human tumour virology

31 March 2020

1 reference

An Address on a Characteristic Organism of Cancer

31 March 2020

1 reference

Cultural properties and pathogenicity of certain microorganisms obtained from various proliferative and neoplastic diseases

31 March 2020

1 reference

Unproven methods of cancer management. Fresh cell therapy

31 March 2020

1 reference

Helicobacter pylori: gastric cancer and beyond

31 March 2020

1 reference

Activation of beta-catenin by carcinogenic Helicobacter pylori

31 March 2020

1 reference

Chronic bacterial and parasitic infections and cancer: a review

31 March 2020

1 reference

Structure, function and diversity of the healthy human microbiome

31 March 2020

1 reference

Honor thy gut symbionts redux

31 March 2020

1 reference

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

31 March 2020

1 reference

ERK activation drives intestinal tumorigenesis in Apc(min/+) mice

31 March 2020

1 reference

Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility

31 March 2020

1 reference

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18

31 March 2020

1 reference

Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors

31 March 2020

1 reference

Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer

31 March 2020

1 reference

Integrative inflammasome activity in the regulation of intestinal mucosal immune responses

31 March 2020

1 reference

Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4.

31 March 2020

1 reference

IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation

31 March 2020

1 reference

A functional role for Nlrp6 in intestinal inflammation and tumorigenesis

31 March 2020

1 reference

Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury

31 March 2020

1 reference

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

31 March 2020

1 reference

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

31 March 2020

1 reference

Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer

31 March 2020

1 reference

Microbial dysbiosis in colorectal cancer (CRC) patients

31 March 2020

1 reference

Towards the human colorectal cancer microbiome

31 March 2020

1 reference

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

31 March 2020

1 reference

Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

31 March 2020

1 reference

Invasive potential of gut mucosa-derived Fusobacterium nucleatum positively correlates with IBD status of the host.

31 March 2020

1 reference

Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment

31 March 2020

1 reference

Fusobacterium nucleatum promotes colorectal carcinogenesis by modulating E-cadherin/β-catenin signaling via its FadA adhesin

31 March 2020

1 reference

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

31 March 2020

1 reference

Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4.

31 March 2020

1 reference

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

31 March 2020

1 reference

Protective role of Toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesis

31 March 2020

1 reference

Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis

31 March 2020

1 reference

Inflammation and cancer: is the link as simple as we think?

31 March 2020

1 reference

An update on the use and investigation of probiotics in health and disease

31 March 2020

1 reference

Lactobacillus acidophilus could modulate the immune response against breast cancer in murine model

31 March 2020

1 reference

Immunoregulatory mechanisms underlying prevention of colitis-associated colorectal cancer by probiotic bacteria

31 March 2020

1 reference

Cross-talk between probiotic bacteria and the host immune system.

31 March 2020

1 reference

Effects of Lactobacillus rhamnosus GG on proliferation and polyamine metabolism in HGC-27 human gastric and DLD-1 colonic cancer cell lines.

31 March 2020

1 reference

Inhibition of proliferation in colon cancer cell lines and harmful enzyme activity of colon bacteria by Bifidobacterium adolescentis SPM0212

31 March 2020

1 reference

A synbiotic combination of resistant starch and Bifidobacterium lactis facilitates apoptotic deletion of carcinogen-damaged cells in rat colon.

31 March 2020

1 reference

Lactobacillus- and bifidobacterium-mediated antigenotoxicity in the colon of rats

31 March 2020

1 reference

Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis

31 March 2020

1 reference

12 December 2020

An experimental biologic approach to the treatment of neoplastic disease; determination of actinomycin in urine and cultures as an aid to diagnosis and prognosis

1 reference

12 December 2020

TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells

1 reference

12 December 2020

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.

1 reference

12 December 2020

Unproven methods of cancer management. Livingston-Wheeler therapy

1 reference

12 December 2020

Chronic bacterial infection and subsequent human carcinogenesis.

1 reference

12 December 2020

Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8(+) T cells resulting in a failure to lyse tumor cells.

1 reference

12 December 2020

Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC3611

1 reference

5 August 2017

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