(Q36193541)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Ming Yi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1

Christophe Cataisson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

12

Giorgio Trinchieri

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Rosalba Salcedo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Shakeeb Hakim

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Lisa Wright

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Robert Stephens

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Ren-Ming Dai

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Lyudmila Lyakh

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Dominik Schenten

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

H Stuart Yuspa

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

language of work or name

English

0 references

publication date

20 August 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

11 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

209

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

1689-1702

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

11 February 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3428947

inferred from PubMed Central ID database lookup

cites work

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IL-36R ligands are potent regulators of dendritic and T cells

1 October 2017

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Oncogenically active MYD88 mutations in human lymphoma

1 October 2017

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Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate

1 October 2017

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Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation

1 October 2017

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TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells.

1 October 2017

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Inhibition of lipocalin 2 impairs breast tumorigenesis and metastasis

1 October 2017

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MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity

1 October 2017

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ELR+ CXC chemokines and oncogenic Ras-mediated tumorigenesis

1 October 2017

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Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications

1 October 2017

1 reference

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Cellular and molecular pathways linking inflammation and cancer

1 October 2017

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Seeking unique and common biological themes in multiple gene lists or datasets: pathway pattern extraction pipeline for pathway-level comparative analysis

1 October 2017

1 reference

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Immunological and inflammatory functions of the interleukin-1 family

1 October 2017

1 reference

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Inducible cutaneous inflammation reveals a protumorigenic role for keratinocyte CXCR2 in skin carcinogenesis

1 October 2017

1 reference

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Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis

1 October 2017

1 reference

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Inflammation and cancer: The oncogene-driven connection

1 October 2017

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NF-kappaB and cancer-identifying targets and mechanisms

1 October 2017

1 reference

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Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis

1 October 2017

1 reference

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Opposing roles of murine duffy antigen receptor for chemokine and murine CXC chemokine receptor-2 receptors in murine melanoma tumor growth

1 October 2017

1 reference

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Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation

1 October 2017

1 reference

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Activation of a nuclear factor kappaB/interleukin-1 positive feedback loop by amphiregulin in human breast cancer cells

1 October 2017

1 reference

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Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice

1 October 2017

1 reference

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Hyperactive Ras in developmental disorders and cancer

1 October 2017

1 reference

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Chemokines and squamous cancer of the head and neck: targets for therapeutic intervention?

1 October 2017

1 reference

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Nuclear factor-kappaB in development, prevention, and therapy of cancer

1 October 2017

1 reference

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The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions

1 October 2017

1 reference

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CXCR2 ligands and G-CSF mediate PKCalpha-induced intraepidermal inflammation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Down-regulation of CXCL5 inhibits squamous carcinogenesis.

1 October 2017

1 reference

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High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras

1 October 2017

1 reference

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CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer

1 October 2017

1 reference

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Modelling cancer in human skin tissue

1 October 2017

1 reference

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Inflammation in epithelial skin tumours: old stories and new ideas

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

The role of interleukin 1 in growth and metastasis of human cancer xenografts

1 October 2017

1 reference

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Proteins with whey-acidic-protein motifs and cancer

1 October 2017

1 reference

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WholePathwayScope: a comprehensive pathway-based analysis tool for high-throughput data

1 October 2017

1 reference

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RalGDS is required for tumor formation in a model of skin carcinogenesis.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Cooperative autocrine and paracrine functions of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in the progression of skin carcinoma cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Nuclear factor-kappaB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

A continuous delivery system of IL-1 receptor antagonist reduces angiogenesis and inhibits tumor development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Activation of cutaneous protein kinase C alpha induces keratinocyte apoptosis and intraepidermal inflammation by independent signaling pathways

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Progress in cutaneous cancer research

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Src family kinases phosphorylate protein kinase C delta on tyrosine residues and modify the neoplastic phenotype of skin keratinocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Paracrine angiogenic loop between head-and-neck squamous-cell carcinomas and macrophages

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Significance analysis of microarrays applied to the ionizing radiation response

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Growth regulated oncogene-alpha expression by murine squamous cell carcinoma promotes tumor growth, metastasis, leukocyte infiltration and angiogenesis by a host CXC receptor-2 dependent mechanism

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

In vivo control of NF-kappa B activation by I kappa B alpha.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 alpha and beta mRNA. Keratinocyte epidermal cell-derived thymocyte-activating factor is identical to interleukin 1.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Molecular mechanisms of mouse skin tumor promotion

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Modulation of interleukin-1 alpha mRNA expression in mouse epidermis by tumor promoters and antagonists

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Ras gene mutation and amplification in human nonmelanoma skin cancers

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Raf-1 addiction in Ras-induced skin carcinogenesis

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1 beta-induced neovascularization and tumor growth.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Protein kinase C alpha-mediated chemotaxis of neutrophils requires NF-kappa B activity but is independent of TNF alpha signaling in mouse skin in vivo

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Depletion of CXCR2 inhibits tumor growth and angiogenesis in a murine model of lung cancer

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Proinflammatory cytokine IL-1 beta promotes tumor growth of Lewis lung carcinoma by induction of angiogenic factors: in vivo analysis of tumor-stromal interaction.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Alterations in murine keratinocyte differentiation induced by activated rasHa genes are mediated by protein kinase C-alpha.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Interleukin-1 alpha mediates phorbol ester-induced inflammation and epidermal hyperplasia.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428947

Analysis of risk factors determining prognosis of cutaneous squamous-cell carcinoma: a prospective study

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20101355

Activated ras Genes Occur in Human Actinic Keratoses, Premalignant Precursors to Squamous Cell Carcinomas

21 January 2018

1 reference

12 December 2020

Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis

1 reference

12 December 2020

Transgenic mice with hematopoietic and lymphoid specific expression of Cre

1 reference

12 December 2020

Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice

1 reference

12 December 2020

Autocrine transforming growth factor alpha is dispensible for v-rasHa-induced epidermal neoplasia: potential involvement of alternate epidermal growth factor receptor ligands

1 reference

12 December 2020

The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20101355

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

22908325

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908325%20AND%20SRC:MED&resulttype=core&format=json