(Q36422870)

14 August 2017

1 reference

title

Modelling cancer in human skin tissue (English)

1 reference

14 August 2017

Paul A Khavari

1

1 reference

PubMed ID

16541145

14 August 2017

language of work or name

English

0 references

publication date

1 April 2006

1 reference

14 August 2017

Nature Reviews Cancer

1 reference

14 August 2017

6

1 reference

14 August 2017

270-280

1 reference

14 August 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1038/nrc1838

14 August 2017

0 references

cites work

Tumour-cell invasion and migration: diversity and escape mechanisms

1 reference

Modelling glandular epithelial cancers in three-dimensional cultures

21 January 2018

1 reference

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

21 January 2018

1 reference

The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

21 January 2018

1 reference

Creation of human tumour cells with defined genetic elements

21 January 2018

1 reference

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

21 January 2018

1 reference

Cutaneous squamous-cell carcinoma

21 January 2018

1 reference

The epidemiology of skin cancer

21 January 2018

1 reference

Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog

21 January 2018

1 reference

CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis

21 January 2018

1 reference

NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.

21 January 2018

1 reference

Type VII collagen is required for Ras-driven human epidermal tumorigenesis.

21 January 2018

1 reference

Use of human tissue to assess the oncogenic activity of melanoma-associated mutations

21 January 2018

1 reference

Application of comparative functional genomics to identify best-fit mouse models to study human cancer

21 January 2018

1 reference

Myc-driven murine prostate cancer shares molecular features with human prostate tumors

21 January 2018

1 reference

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis.

21 January 2018

1 reference

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

21 January 2018

1 reference

Cancer in rodents: does it tell us about cancer in humans?

21 January 2018

1 reference

Distinct requirements for Ras oncogenesis in human versus mouse cells

21 January 2018

1 reference

Modelling the molecular circuitry of cancer

21 January 2018

1 reference

Controls of hair follicle cycling

21 January 2018

1 reference

New insights into skin structure: scratching the surface

21 January 2018

1 reference

NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK.

21 January 2018

1 reference

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

21 January 2018

1 reference

Photocarcinogenesis in human adult skin grafts

21 January 2018

1 reference

Sunlight and the onset of skin cancer

21 January 2018

1 reference

Stromal fibroblasts in cancer initiation and progression

21 January 2018

1 reference

Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice

21 January 2018

1 reference

Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter

21 January 2018

1 reference

Probing keratinocyte and differentiation specificity of the human K5 promoter in vitro and in transgenic mice

21 January 2018

1 reference

Tissue- and stratum-specific expression of the human involucrin promoter in transgenic mice

21 January 2018

1 reference

Identification of a calcium-inducible, epidermal-specific regulatory element in the 3'-flanking region of the human keratin 1 gene

21 January 2018

1 reference

Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

21 January 2018

1 reference

Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease

21 January 2018

1 reference

Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis

21 January 2018

1 reference

Corrective gene transfer in the human skin disorder lamellar ichthyosis

21 January 2018

1 reference

Systemic distribution of apolipoprotein E secreted by grafts of epidermal keratinocytes: implications for epidermal function and gene therapy

21 January 2018

1 reference

Fibroblasts and dermal gene therapy: a minireview

21 January 2018

1 reference

Induction of melanoma phenotypes in human skin by growth factors and ultraviolet B.

21 January 2018

1 reference

Lentivectors for regulated and reversible cutaneous gene delivery

21 January 2018

1 reference

In vivo restoration of laminin 5 beta 3 expression and function in junctional epidermolysis bullosa

21 January 2018

1 reference

Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue

21 January 2018

1 reference

Stable nonviral genetic correction of inherited human skin disease

21 January 2018

1 reference

Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis

21 January 2018

1 reference

Mammalian gene targeting with designed zinc finger nucleases

21 January 2018

1 reference

Human dermal microvascular endothelial cells form vascular analogs in cultured skin substitutes after grafting to athymic mice.

21 January 2018

1 reference

Melanoma incidence trends

21 January 2018

1 reference

Basal cell nevus syndrome

21 January 2018

1 reference

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

21 January 2018

1 reference

Basal cell carcinomas in mice overexpressing sonic hedgehog

21 January 2018

1 reference

Basal cell carcinomas in mice overexpressing Gli2 in skin

21 January 2018

1 reference

Activating Smoothened mutations in sporadic basal-cell carcinoma

21 January 2018

1 reference

Sonic hedgehog opposes epithelial cell cycle arrest

21 January 2018

1 reference

Cancer in xeroderma pigmentosum and related disorders of DNA repair

21 January 2018

1 reference

Dyskeratosis congenita -- a disease of dysfunctional telomere maintenance

21 January 2018

1 reference

Epidermolysis bullosa and cancer

21 January 2018

1 reference

Ras gene mutation and amplification in human nonmelanoma skin cancers

21 January 2018

1 reference

Ras activation in human breast cancer

21 January 2018

1 reference

RAS is regulated by the let-7 microRNA family

21 January 2018

1 reference

CDK4 regulation by TNFR1 and JNK is required for NF-kappaB-mediated epidermal growth control

21 January 2018

1 reference

Enhanced malignant tumorigenesis in Cdk4 transgenic mice

21 January 2018

1 reference

Melanoma genetics and the development of rational therapeutics

21 January 2018

1 reference

Genetic progression of metastatic melanoma.

21 January 2018

1 reference

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

Progressive increase in telomerase activity from benign melanocytic conditions to malignant melanoma

21 January 2018

1 reference

Chromosomal imbalances in primary and metastatic melanomas: over-representation of essential telomerase genes

21 January 2018

1 reference

Rules for making human tumor cells

21 January 2018

1 reference

Transformation of human and murine fibroblasts without viral oncoproteins

21 January 2018

1 reference

Targeting RAS signalling pathways in cancer therapy

21 January 2018

1 reference

Understanding Ras: 'it ain't over 'til it's over'.

21 January 2018

1 reference

Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation

21 January 2018

1 reference

Chromosomal aberrations in squamous cell carcinoma and solar keratoses revealed by comparative genomic hybridization.

21 January 2018

1 reference

Fluorescence in situ hybridization (FISH) evaluation of chromosomes 6, 7, 9 and 10 throughout human melanocytic tumorigenesis

21 January 2018

1 reference

21 January 2018

Inflammation and cancer

1 reference

Spontaneous keratinocyte cell lines representing early and advanced stages of malignant transformation of the epidermis

21 January 2018

1 reference

Skin cancer following transplantation: the Israel Penn International Transplant Tumor Registry experience

21 January 2018

1 reference

Distinct sets of genetic alterations in melanoma

21 January 2018

1 reference

Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma

21 January 2018

1 reference

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

21 January 2018

1 reference

High frequency of BRAF mutations in nevi

21 January 2018

1 reference

BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

1 reference

Expression and topography of integrins and basement membrane proteins in epidermal carcinomas: basal but not squamous cell carcinomas display loss of alpha 6 beta 4 and BM-600/nicein

21 January 2018

1 reference

Upping the ante on antibodies.

21 January 2018

1 reference

Cancer. An anchor for tumor cell invasion.

21 January 2018

1 reference

Reconstruction of functionally normal and malignant human breast tissues in mice

21 January 2018

1 reference

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

21 January 2018

1 reference

Technologically advanced cancer modeling in mice

21 January 2018

1 reference

Squamous cell carcinoma arising in previously burned or irradiated skin

21 January 2018

1 reference

Targets for molecular therapy of skin cancer

21 January 2018

1 reference

21 January 2018

1 reference

Nonmelanoma skin cancer in the United States: incidence.

21 January 2018

1 reference

Species- and cell type-specific requirements for cellular transformation

31 March 2020

1 reference

Selective uptake and sustained expression of AAV vectors following subcutaneous delivery

31 March 2020

1 reference

The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted

31 March 2020

1 reference

Sustainable systemic delivery via a single injection of lentivirus into human skin tissue

31 March 2020

1 reference

Cytokine gene expression in epidermis with biological effects following injection of naked DNA

31 March 2020

1 reference

Evaluation of human skin reconstituted from composite grafts of cultured keratinocytes and human acellular dermis transplanted to athymic mice.

31 March 2020

1 reference

Telomerized human microvasculature is functional in vivo

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRC1838

1 reference

PubMed ID

16541145

Dimensions Publication ID

14 August 2017

0 references

1 reference

PubMed ID

16541145