(Q44303541)

English

ATP2B1 gene Silencing Increases Insulin Sensitivity through Facilitating Akt Activation via the Ca2+/calmodulin Signaling Pathway and Ca2+-associated eNOS Activation in Endothelial Cells.

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scholarly article

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8 April 2020

ATP2B1 gene Silencing Increases Insulin Sensitivity through Facilitating Akt Activation via the Ca2+/calmodulin Signaling Pathway and Ca2+-associated eNOS Activation in Endothelial Cells (English)

1 reference

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8 April 2020

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0 references

AKT serine/threonine kinase 1

1 reference

GOA release 2020-03-11

ATPase plasma membrane Ca2+ transporting 1

1 reference

GOA release 2020-03-11

calmodulin binding

1 reference

GOA release 2020-03-11

1

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8 April 2020

author name string

Ji-Yi Xia

2

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8 April 2020

Shao-Wei Chen

3

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8 April 2020

Chen-Lin Gao

4

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8 April 2020

Guan-Nan Liang

5

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8 April 2020

Xue-Mei He

6

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8 April 2020

Jian Wu

7

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8 April 2020

Chun-Xia Jiang

8

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8 April 2020

Xin Liu

9

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8 April 2020

Wei Huang

10

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8 April 2020

Qin Wan

11

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8 April 2020

Yong Xu

12

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8 April 2020

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publication date

5 September 2017

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8 April 2020

International Journal of Biological Sciences

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8 April 2020

13

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8 April 2020

1203-1212

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8 April 2020

9

1 reference

Europe PubMed Central

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8 April 2020

Selective Insulin Resistance and the Development of Cardiovascular Diseases in Diabetes: The 2015 Edwin Bierman Award Lecture

1 reference

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25 May 2018

Plasma membrane calcium ATPases (PMCAs) as potential targets for the treatment of essential hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

PKCδ inhibition normalizes the wound-healing capacity of diabetic human fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

SKF-96365 activates cytoprotective autophagy to delay apoptosis in colorectal cancer cells through inhibition of the calcium/CaMKIIγ/AKT-mediated pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Structural and Biophysical Characterization of the Interactions between Calmodulin and the Pleckstrin Homology Domain of Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Endothelial nitric oxide synthase in the microcirculation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

The plasma membrane calcium pump: new ways to look at an old enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Insulin-stimulated leptin secretion requires calcium and PI3K/Akt activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Male-specific genetic effect on hypertension and metabolic disorders.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Induction of vascular insulin resistance and endothelin-1 expression and acceleration of atherosclerosis by the overexpression of protein kinase C-β isoform in the endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Silencing of Atp2b1 increases blood pressure through vasoconstriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Structural diversity of calmodulin binding to its target sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Mice lacking hypertension candidate gene ATP2B1 in vascular smooth muscle cells show significant blood pressure elevation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Genome-wide association study identifies eight loci associated with blood pressure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Genome-wide association study of blood pressure and hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Calmodulin modulates Akt activity in human breast cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

The plasma membrane Ca2+ ATPase of animal cells: structure, function and regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Ca(2+)/calmodulin directly interacts with the pleckstrin homology domain of AKT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Cardiovascular actions of insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Calmodulin-mediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Calcium signalling: dynamics, homeostasis and remodelling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Substrate binding and calmodulin binding to endothelial nitric oxide synthase coregulate its enzymatic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Dependence of augmentation of arterial endothelial cell expression of plasminogen activator inhibitor type 1 by insulin on soluble factors released from vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Asymptomatic atherosclerosis and insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

Stimulation of endothelin-1 gene expression by insulin in endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

25 May 2018

The Interplay between Calmodulin and Membrane Interactions with the Pleckstrin Homology Domain of Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

15 August 2018

Exogenous Bradykinin Inhibits Tissue Factor Induction and Deep Vein Thrombosis via Activating the eNOS/Phosphoinositide 3-Kinase/Akt Signaling Pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

15 August 2018

Blood pressure and hypertension are associated with 7 loci in the Japanese population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

15 August 2018

A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

15 August 2018

Induction of claudin-4 by nonsteroidal anti-inflammatory drugs and its contribution to their chemopreventive effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

15 August 2018

Neuronal survival induced by neurotrophins requires calmodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

15 August 2018

Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5666335

15 August 2018

Impaired nitric oxide production and increased blood pressure in systemic heterozygous ATP2B1 null mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29104511

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circular dichroism and 1H NMR studies on the structures of peptides derived from the calmodulin-binding domains of inducible and endothelial nitric-oxide synthase in solution and in complex with calmodulin. Nascent alpha-helical structures are stabi

1 reference

https://pubmed.ncbi.nlm.nih.gov/29104511

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.7150/IJBS.19666

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8 April 2020

1 reference

Europe PubMed Central

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8 April 2020

1 reference

Europe PubMed Central

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8 April 2020

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