(Q44408944)

2 December 2017

The RB family is required for the self-renewal and survival of human embryonic stem cells (English)

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human embryonic stem cell

2 December 2017

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3

Julien Sage

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2 December 2017

Jamie F Conklin

1

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PubMed ID

23212373

2 December 2017

Julie Baker

series ordinal

2

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PubMed ID

23212373

2 December 2017

language of work or name

English

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publication date

1 January 2012

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2 December 2017

Nature Communications

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2 December 2017

3

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2 December 2017

1244

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https://scigraph.springernature.com/pub.10.1038/ncomms2254

2 December 2017

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cites work

Retinal progenitor cells, differentiation, and barriers to cell cycle reentry

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12 December 2020

A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression

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12 December 2020

Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells.

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12 December 2020

Rb regulates fate choice and lineage commitment in vivo

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12 December 2020

Phosphorylation dynamics during early differentiation of human embryonic stem cells.

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12 December 2020

Cell cycle features of primate embryonic stem cells.

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12 December 2020

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status

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12 December 2020

Cre-lox-regulated conditional RNA interference from transgenes

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12 December 2020

A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members

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12 December 2020

Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells

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12 December 2020

Division and apoptosis of E2f-deficient retinal progenitors

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12 December 2020

Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen

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12 December 2020

Differentiation is coupled to changes in the cell cycle regulatory apparatus of human embryonic stem cells.

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12 December 2020

DiRE: identifying distant regulatory elements of co-expressed genes

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12 December 2020

Rb is critical in a mammalian tissue stem cell population

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12 December 2020

A small-molecule E2F inhibitor blocks growth in a melanoma culture model

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12 December 2020

Signalling, cell cycle and pluripotency in embryonic stem cells

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12 December 2020

Pluripotency in the embryo and in culture

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12 December 2020

Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F.

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12 December 2020

Deficiency of Retinoblastoma gene in mouse embryonic stem cells leads to genetic instability

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12 December 2020

Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells

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12 December 2020

Factors regulating pluripotency and differentiation in early mammalian embryos and embryo-derived stem cells.

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12 December 2020

Isolation and transcriptional profiling of purified hepatic cells derived from human embryonic stem cells

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12 December 2020

The retinoblastoma tumor suppressor and stem cell biology

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12 December 2020

Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation

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12 December 2020

A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A.

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12 December 2020

T antigen transgenic mouse models

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12 December 2020

Keeping an eye on retinoblastoma control of human embryonic stem cells

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12 December 2020

Loss of pRB causes centromere dysfunction and chromosomal instability

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12 December 2020

Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells.

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12 December 2020

Cell cycle control of embryonic stem cells

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12 December 2020

T-antigen mutant activities in vivo: roles of p53 and pRB binding in tumorigenesis of the choroid plexus

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12 December 2020

Retinoblastoma Tumor Suppressor: Analyses of Dynamic Behavior in Living Cells Reveal Multiple Modes of Regulation

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12 December 2020

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

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12 December 2020

Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive

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12 December 2020

G1 to S phase cell cycle transition in somatic and embryonic stem cells.

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12 December 2020

Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency

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12 December 2020

A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity

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12 December 2020

Survival responses of human embryonic stem cells to DNA damage

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12 December 2020

Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family

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12 December 2020

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

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12 December 2020

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling

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12 December 2020

RB: mitotic implications of a tumour suppressor

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12 December 2020

Tandem E2F binding sites in the promoter of the p107 cell cycle regulator control p107 expression and its cellular functions

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12 December 2020

Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells

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12 December 2020

Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells

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12 December 2020

Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells

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12 December 2020

RB1, development, and cancer

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12 December 2020

RB regulates pancreas development by stabilizing Pdx1

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12 December 2020

Direct reprogramming of fibroblasts into epiblast stem cells.

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12 December 2020

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

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12 December 2020

WebGestalt: an integrated system for exploring gene sets in various biological contexts

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12 December 2020

The tumorigenicity of human embryonic and induced pluripotent stem cells

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12 December 2020

Therapeutic potential of embryonic stem cells

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12 December 2020

New cell lines from mouse epiblast share defining features with human embryonic stem cells

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12 December 2020

Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells

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12 December 2020

Proapoptotic function of the retinoblastoma tumor suppressor protein

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12 December 2020

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

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12 December 2020

Differences between human and mouse embryonic stem cells

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12 December 2020

Identifiers

DOI

10.1038/NCOMMS2254

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2 December 2017

0 references

1 reference

PubMed ID

23212373