(Q44422869)

2 December 2017

title

BCL-2 and BCL-XL restrict lineage choice during hematopoietic differentiation (English)

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2 December 2017

2

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2 December 2017

4

Harald von Boehmer

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2 December 2017

5

David M Hockenbery

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2 December 2017

Loralee Haughn

1

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2 December 2017

Deborah K Morrison

series ordinal

3

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2 December 2017

language of work or name

English

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publication date

28 April 2003

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Journal of Biological Chemistry

2 December 2017

published in

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2 December 2017

volume

278

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2 December 2017

issue

27

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2 December 2017

page(s)

25158-25165

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Self-renewal, differentiation or death: regulation and manipulation of hematopoietic stem cell fate

2 December 2017

cites work

1 reference

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Double identity for proteins of the Bcl-2 family

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The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

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Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2.

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Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

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Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice

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Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

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Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice

21 January 2018

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Bcl-2 promotes regeneration of severed axons in mammalian CNS

21 January 2018

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Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

21 January 2018

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Interleukin 2-mediated uncoupling of T cell receptor alpha/beta from CD3 signaling

21 January 2018

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Comparative analysis of genetically modified dendritic cells and tumor cells as therapeutic cancer vaccines

21 January 2018

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Bcl-2 targets the protein kinase Raf-1 to mitochondria

21 January 2018

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The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4

21 January 2018

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Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

21 January 2018

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The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors

21 January 2018

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Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

21 January 2018

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Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association

21 January 2018

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Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors

21 January 2018

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p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function

21 January 2018

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Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors

21 January 2018

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BAG-1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release.

21 January 2018

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Mammalian protein RAP46: an interaction partner and modulator of 70 kDa heat shock proteins

21 January 2018

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The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome

21 January 2018

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VEGF(165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition

21 January 2018

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bcl-x prevents apoptotic cell death of both primitive and definitive erythrocytes at the end of maturation

21 January 2018

1 reference

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Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival

21 January 2018

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Development of oxidase 'priming' in maturing HL60 cells: correlation with protein expression and tyrosine phosphorylation

21 January 2018

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Modulation of p210(BCR-ABL) activity in transduced primary human hematopoietic cells controls lineage programming

21 January 2018

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Neuronal differentiation of PC12 cells as a result of prevention of cell death by bcl-2

21 January 2018

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Differential expression of bcl-2 homologs in human CD34(+) hematopoietic progenitor cells induced to differentiate into erythroid or granulocytic cells

21 January 2018

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Retroviral vectors for production of interleukin-12 in the bone marrow to induce a graft-versus-leukemia effect

21 January 2018

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Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M212849200

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2 December 2017

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