(Q44429634)

2 December 2017

title

Intracellular mediators of erucylphosphocholine-induced apoptosis (English)

1 reference

signal transducing adaptor protein

2 December 2017

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730676

30 December 2023

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

30 December 2023

4

Claus Belka

1 reference

2 December 2017

1

Verena Jendrossek

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730676

30 December 2023

author name string

Ilka Müller

2

1 reference

2 December 2017

Hansjörg Eibl

3

1 reference

2 December 2017

language of work or name

English

0 references

publication date

1 May 2003

1 reference

full work available at URL

2 December 2017

https://www.nature.com/articles/1206355.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

https://www.nature.com/articles/1206355

30 December 2023

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

30 December 2023

1 reference

2 December 2017

volume

22

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2 December 2017

issue

17

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2 December 2017

page(s)

2621-2631

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206355

2 December 2017

exact match

0 references

cites work

Anti-apoptotic Bcl-2 proteins: structure, function and relevance for radiation biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

Hexadecylphosphocholine differs from conventional cytostatic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

Caspase activation: the induced-proximity model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

A dose-finding study of miltefosine (hexadecylphosphocholine) in patients with metastatic solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

Induction of ceramide-mediated apoptosis by the anticancer phospholipid analog, hexadecylphosphocholine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Effects of hexadecylphosphocholine on membrane phospholipid metabolism in human tumour cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Self-association of the Death Domains of the p55 Tumor Necrosis Factor (TNF) Receptor and Fas/APO1 Prompts Signaling for TNF and Fas/APO1 Effects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Initiator caspases in apoptosis signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

An alternative way of CD4 and CD8 association with protein kinases of the Src family.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

The kiss of death: promises and failures of death receptors and ligands in cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Modulation of phospholipase D by hexadecylphosphorylcholine: a putative novel mechanism for its antitumoral activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

2-Chloro-2'-deoxyadenosine induces apoptosis through the Fas/Fas ligand pathway in human leukemia cell line MOLT-4.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Membrane damage in leukemic cells induced by ether and ester lipids: an electron microscopic study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Radiation sensitivity and apoptosis in human lymphoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

New insights in the role of Bcl-2 Bcl-2 and the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Caspases: intracellular signaling by proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Phase II study of miltefosine 6% solution as topical treatment of skin metastases in breast cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Opposite effect of miltefosine on the antineoplastic activity and haematological toxicity of cyclophosphamide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Hexadecylphosphocholine in the topical treatment of skin metastases in breast cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206355

7 January 2021

Effects of hexadecylphosphocholine on thrombocytopoiesis

7

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Synergistic cytotoxic effects of ether phospholipid analogues and ionizing radiation in human carcinoma cells

30 December 2023

8

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system.

30 December 2023

12

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

30 December 2023

14

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Miltefosine as a topical treatment for cutaneous metastases in breast carcinoma

30 December 2023

16

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Erucylphosphocholine: pharmacokinetics, biodistribution and CNS-accumulation in the rat after intravenous administration

30 December 2023

21

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid-induced apoptosis

30 December 2023

26

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Involvement of c-Jun NH2-terminal kinase activation and c-Jun in the induction of apoptosis by the ether phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine

30 December 2023

28

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Combination effects of alkylphosphocholines and gemcitabine in malignant and normal hematopoietic cells

30 December 2023

29

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

CD95 Signaling via Ceramide-rich Membrane Rafts

30 December 2023

30

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Ceramides modulate protein kinase C activity and perturb the structure of Phosphatidylcholine/Phosphatidylserine bilayers

30 December 2023

32

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Human urinary bladder carcinoma cell lines respond to treatment with alkylphosphocholines

30 December 2023

36

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Alkylphosphocholines induce apoptosis in HL-60 and U-937 leukemic cells

30 December 2023

37

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Killing tumour cells by alkylphosphocholines: evidence for involvement of CD95.

30 December 2023

43

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

The ether lipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine induces expression of fos and jun proto-oncogenes and activates AP-1 transcription factor in human leukaemic cells

30 December 2023

47

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

30 December 2023

48

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Bcl-2 overexpression prevents apoptosis induced by ceramidase inhibitors in malignant melanoma and HaCaT keratinocytes.

30 December 2023

54

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Apoptosis signaling by death receptors.

30 December 2023

64

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

Death by a thousand cuts: an ever increasing list of caspase substrates

30 December 2023

68

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206355

30 December 2023

Identifiers

1 reference

Dimensions Publication ID

2 December 2017

1016754894

0 references

1 reference