(Q43583285)

24 November 2017

Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation (English)

1 reference

24 November 2017

1 reference

Stepczynska A

1

1 reference

24 November 2017

Lauber K

2

1 reference

24 November 2017

Engels IH

3

1 reference

24 November 2017

Janssen O

4

1 reference

24 November 2017

Kabelitz D

5

1 reference

24 November 2017

Wesselborg S

6

1 reference

24 November 2017

Schulze-Osthoff K

7

1 reference

24 November 2017

language of work or name

English

0 references

publication date

1 March 2001

1 reference

24 November 2017

1 reference

24 November 2017

20

1 reference

24 November 2017

1193-1202

1 reference

24 November 2017

10

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204221

24 November 2017

0 references

cites work

Control of apoptosis by Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Induction of a Common Pathway of Apoptosis by Staurosporine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

1 reference

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Inhibition of the protein kinase C pathway promotes anti-CD95-induced apoptosis in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Analogs of staurosporine: potential anticancer drugs?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

The staurosporine analog, Ro-31-8220, induces apoptosis independently of its ability to inhibit protein kinase C

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Induction of cell death via Fas (CD95, Apo-1) may be associated with but is not dependent on Fas-induced tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Different susceptibility of protein kinases to staurosporine inhibition. Kinetic studies and molecular bases for the resistance of protein kinase CK2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

IkappaB kinases alpha and beta show a random sequential kinetic mechanism and are inhibited by staurosporine and quercetin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Cell nucleus and DNA fragmentation are not required for apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Apoptosis signaling by death receptors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c rel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Affinity labeling displays the stepwise activation of ICE-related proteases by Fas, staurosporine, and CrmA-sensitive caspase-8

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204221

1 reference

Dimensions Publication ID

24 November 2017

0 references

1 reference