(Q44430058)

2 December 2017

Increased hyaluronan content and stromal cell CD44 associate with HER2 positivity and poor prognosis in human breast cancer (English)

1 reference

2 December 2017

6

Arto Mannermaa

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2 December 2017

5

Ylermi Soini

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2 December 2017

3

Veli-Matti Kosma

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2 December 2017

Päivi Auvinen

1

1 reference

2 December 2017

Raija Tammi

2

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2 December 2017

Reijo Sironen

4

1 reference

2 December 2017

Ritva Tumelius

7

1 reference

2 December 2017

Eliisa Uljas

8

1 reference

2 December 2017

Markku Tammi

9

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2 December 2017

language of work or name

English

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publication date

20 July 2012

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International Journal of Cancer

2 December 2017

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2 December 2017

132

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2 December 2017

3

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2 December 2017

531-539

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Hyaluronan in human tumors: pathobiological and prognostic messages from cell-associated and stromal hyaluronan

2 December 2017

1 reference

Hyaluronan in human malignancies

21 January 2018

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Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival

21 January 2018

1 reference

Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncogenic malignant transformation.

21 January 2018

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Hyaluronan: a critical component of epithelial-mesenchymal and epithelial-carcinoma transitions

21 January 2018

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Hyaluronan-CD44 interaction with protein kinase C(epsilon) promotes oncogenic signaling by the stem cell marker Nanog and the Production of microRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemothera

21 January 2018

1 reference

Cross-talk between human monocytes and cancer cells during reactive oxygen intermediates generation: the essential role of hyaluronan

21 January 2018

1 reference

Angiogenic oligosaccharides of hyaluronan induce multiple signaling pathways affecting vascular endothelial cell mitogenic and wound healing responses

21 January 2018

1 reference

Significance of tumor-associated stroma in promotion of intratumoral lymphangiogenesis: pivotal role of a hyaluronan-rich tumor microenvironment

21 January 2018

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Signaling properties of hyaluronan receptors

21 January 2018

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Lymphocyte recognition of high endothelium: antibodies to distinct epitopes of an 85-95-kD glycoprotein antigen differentially inhibit lymphocyte binding to lymph node, mucosal, or synovial endothelial cells

21 January 2018

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21 January 2018

The CD44 protein family.

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The cell adhesion molecule, GP116, is a new CD44 variant (ex14/v10) involved in hyaluronic acid binding and endothelial cell proliferation

21 January 2018

1 reference

Prognostic value of CD44 variant expression in primary breast cancer

21 January 2018

1 reference

Hyaluronan-CD44 Interactions in Cancer: Paradoxes and Possibilities

21 January 2018

1 reference

Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells

21 January 2018

1 reference

Tumor cells enhance their own CD44 cleavage and motility by generating hyaluronan fragments

21 January 2018

1 reference

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 January 2018

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Molecular mechanisms underlying ErbB2/HER2 action in breast cancer

21 January 2018

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Increasing CD44+/CD24(-) tumor stem cells, and upregulation of COX-2 and HDAC6, as major functions of HER2 in breast tumorigenesis

21 January 2018

1 reference

Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzumab, as adjuvant treatments of breast cancer: final results of the FinHer Trial

21 January 2018

1 reference

Adjuvant trastuzumab in HER2-positive breast cancer

21 January 2018

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Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: a 4-year follow-up of a randomised controlled trial.

21 January 2018

1 reference

Four-year follow-up of trastuzumab plus adjuvant chemotherapy for operable human epidermal growth factor receptor 2-positive breast cancer: joint analysis of data from NCCTG N9831 and NSABP B-31.

21 January 2018

1 reference

Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells.

21 January 2018

1 reference

Regulation of MDR1 expression and drug resistance by a positive feedback loop involving hyaluronan, phosphoinositide 3-kinase, and ErbB2.

21 January 2018

1 reference

Heregulin-mediated ErbB2-ERK signaling activates hyaluronan synthases leading to CD44-dependent ovarian tumor cell growth and migration

21 January 2018

1 reference

The human hyaluronan synthase 2 gene is a primary retinoic acid and epidermal growth factor responding gene

21 January 2018

1 reference

Hyaluronan-induced masking of ErbB2 and CD44-enhanced trastuzumab internalisation in trastuzumab resistant breast cancer

21 January 2018

1 reference

Downregulated CD44 and hyaluronan expression in vulvar intraepithelial neoplasia and squamous cell carcinomas

21 January 2018

1 reference

Two novel functions of hyaluronidase-2 (Hyal2) are formation of the glycocalyx and control of CD44-ERM interactions

21 January 2018

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Inhibition of Functional Hyaluronan-CD44 Interactions in CD133-positive Primary Human Ovarian Carcinoma Cells by Small Hyaluronan Oligosaccharides

21 January 2018

1 reference

CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

21 January 2018

1 reference

Silencing of hyaluronan synthase 2 suppresses the malignant phenotype of invasive breast cancer cells

21 January 2018

1 reference

Inhibition of hyaluronan synthesis in breast cancer cells by 4-methylumbelliferone suppresses tumorigenicity in vitro and metastatic lesions of bone in vivo

21 January 2018

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Enzymatic depletion of tumor hyaluronan induces antitumor responses in preclinical animal models

21 January 2018

1 reference

Pooled analysis of prospective cohort studies on height, weight, and breast cancer risk

21 January 2018

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Cellular content of UDP-N-acetylhexosamines controls hyaluronan synthase 2 expression and correlates with O-linked N-acetylglucosamine modification of transcription factors YY1 and SP1.

21 January 2018

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Methyl-beta-cyclodextrin suppresses hyaluronan synthesis by down-regulation of hyaluronan synthase 2 through inhibition of Akt.

21 January 2018

1 reference

Hyperglycemic conditions modulate connective tissue reorganization by human vascular smooth muscle cells through stimulation of hyaluronan synthesis.

21 January 2018

1 reference

Cancer cell metabolism: Warburg and beyond

21 January 2018

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Prospective study on the role of glucose metabolism in breast cancer occurrence.

21 January 2018

1 reference

Lactate stimulates fibroblast expression of hyaluronan and CD44: the Warburg effect revisited

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.27707

1 reference

2 December 2017

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