(Q44435409)

English

Oxidant regulation of gene expression and neural tube development: Insights gained from diabetic pregnancy on molecular causes of neural tube defects

scientific article published on March 26, 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 December 2017

Oxidant regulation of gene expression and neural tube development: Insights gained from diabetic pregnancy on molecular causes of neural tube defects (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

internal medicine

1 reference

10.1007/S00125-003-1063-2

https://api.crossref.org/works/10.1007/S00125-003-1063-2

1 January 2024

Rakesh P. Patel

5

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R. Patel

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12739027

1 January 2024

6

object named as

M. R. Loeken

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12739027

1 January 2024

author name string

T. I. Chang

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12739027

1 January 2024

M. Horal

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12739027

1 January 2024

S. K. Jain

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12739027

1 January 2024

F. Wang

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12739027

1 January 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12739027

1 January 2024

publication date

26 March 2003

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

full work available at URL

https://link.springer.com/content/pdf/10.1007/s00125-003-1063-2.pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12739027

1 January 2024

http://link.springer.com/content/pdf/10.1007/s00125-003-1063-2.pdf

Portable Document Format

1 reference

10.1007/S00125-003-1063-2

https://api.crossref.org/works/10.1007/S00125-003-1063-2

1 January 2024

http://link.springer.com/article/10.1007/s00125-003-1063-2/fulltext.html

1 reference

10.1007/S00125-003-1063-2

https://api.crossref.org/works/10.1007/S00125-003-1063-2

1 January 2024

http://link.springer.com/content/pdf/10.1007/s00125-003-1063-2

1 reference

10.1007/S00125-003-1063-2

https://api.crossref.org/works/10.1007/S00125-003-1063-2

1 January 2024

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

46

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

538-545

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-003-1063-2

0 references

Epidemiological analysis of outcomes of pregnancy in diabetic mothers: identification of the most characteristic and most frequent congenital anomalies

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Malformations in infants of diabetic mothers occur before the seventh gestational week. Implications for treatment

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Malformations in infants of diabetic mothers

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Level of glycemia and perinatal outcome in pregestational diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Patterns of congenital anomalies and relationship to initial maternal fasting glucose levels in pregnancies complicated by type 2 and gestational diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Developmental damage, increased lipid peroxidation, diminished cyclooxygenase-2 gene expression, and lowered prostaglandin E2 levels in rat embryos exposed to a diabetic environment.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Temporal expression of genes encoding free radical-metabolizing enzymes is associated with higher mRNA levels during in utero development in mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Antioxidants diminish developmental damage induced by high glucose and cyclooxygenase inhibitors in rat embryos in vitro.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Vitamin E decreases the occurrence of malformations in the offspring of diabetic rats

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Vitamin C supplementation of the maternal diet reduces the rate of malformation in the offspring of diabetic rats.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Dietary vitamin E prophylaxis and diabetic embryopathy: morphologic and biochemical analysis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Pregnant diabetic rats fed the antioxidant butylated hydroxytoluene show decreased occurrence of malformations in offspring

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Teratogenic effects of diabetes mellitus in the rat. Prevention by vitamin E.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Neural tube defects in embryos of diabetic mice: role of the Pax-3 gene and apoptosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Evidence that elevated glucose causes altered gene expression, apoptosis, and neural tube defects in a mouse model of diabetic pregnancy.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Maternal diabetes: an independent risk factor for major cardiovascular malformations with increased mortality of affected infants

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Role for mitochondrial oxidants as regulators of cellular metabolism

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Redox regulation of Cdc25C.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Identification of redox/repair protein Ref-1 as a potent activator of p53

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Cellular oxidative stress and the control of apoptosis by wild-type p53, cytotoxic compounds, and cytokines

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

A role for mitochondria as potential regulators of cellular life span

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Homocysteine accelerates endothelial cell senescence.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Folate protects against oxidative modification of human LDL.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-kappaB in human Hep G2 cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Biochemical toxicology of chemical teratogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Modulation of TCDD-induced fetotoxicity and oxidative stress in embryonic and placental tissues of C57BL/6J mice by vitamin E succinate and ellagic acid.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Prepregnant weight in relation to risk of neural tube defects

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Risk of neural tube defect-affected pregnancies among obese women

1 reference

https://api.crossref.org/works/10.1007%2FS00125-003-1063-2

21 January 2018

Congenital malformations among infants whose mothers had gestational diabetes or preexisting diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of diabetes-associated embryopathy by overexpression of the free radical scavenger copper zinc superoxide dismutase in transgenic mouse embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Migration of cardiac neural crest cells in Splotch embryos.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin E: Substrate-Dependent Growth Effect on Cells in Culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of oxidant-sensitive proteins: TNF-alpha induces protein glutathiolation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Pax-3- and neuroectoderm-inducing activities during differentiation of P19 embryonal carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disorders of the developing nervous system of vitamin E-deficient rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox regulation of thyroid-transcription factors, Pax-8 and TTF-1, is involved in their increased DNA-binding activities by thyrotropin in rat thyroid FRTL-5 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of glutathione depletion and oxidative stress in early embryogenesis in glucose-induced rat embryo culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythrocyte membrane lipid peroxidation and glycosylated hemoglobin in diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kappa B: studies with isolated mitochondri

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of erythrocyte antioxidant enzyme activities and embryologic level of neural tube defects

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes mellitus during pregnancy and the risks for specific birth defects: a population-based case-control study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Congenital anomalies among infants of diabetic mothers. Etiology, prevention, prenatal diagnosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycaemic control during early pregnancy and fetal malformations in women with type I diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of free radicals in cancer and atherosclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Teratogens and craniofacial malformations: relationships to cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose metabolism in separated embryos and investing membranes during organogenesis in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp2H) mutant

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of [14C]glucose by postimplantation mouse embryos in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetic pregnancy and perinatal morbidity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycemic control and spontaneous abortion in insulin-dependent diabetic women

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered metabolism and superoxide generation in neural tissue of rat embryos exposed to high glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of CFTR chloride channels by calyculin A and genistein

15

1 reference

10.1007/S00125-003-1063-2

https://api.crossref.org/works/10.1007/S00125-003-1063-2

1 January 2024

Molecular Pharmacology

37

48

825

author name string

Garcia-Ruiz

publication date

1995

1 reference

10.1007/S00125-003-1063-2

https://api.crossref.org/works/10.1007/S00125-003-1063-2

1 January 2024

Identifiers

10.1007/S00125-003-1063-2

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

ResearchGate publication ID

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