(Q44443761)

English

Alternative splicing and differential expression of the islet autoantigen IGRP between pancreas and thymus contributes to immunogenicity of pancreatic islets but not diabetogenicity in humans

scientific article published on 13 September 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Alternative splicing and differential expression of the islet autoantigen IGRP between pancreas and thymus contributes to immunogenicity of pancreatic islets but not diabetogenicity in humans (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

0 references

alternative mRNA splicing, via spliceosome

1 reference

based on heuristic

inferred from title

Arno R van der Slik

object named as

Arno R van der Slik

4

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author name string

V Martijn de Jong

1

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Joana R F Abreu

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Annemarie A Verrijn Stuart

3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Katrijn Verhaeghen

5

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Marten A Engelse

6

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Bianca Blom

7

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Frank J T Staal

8

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Frans K Gorus

9

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Bart O Roep

10

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

publication date

13 September 2013

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Europe PubMed Central

PubMed publication ID

3 December 2017

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

56

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Europe PubMed Central

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3 December 2017

12

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3 December 2017

2651-2658

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Europe PubMed Central

PubMed publication ID

3 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-013-3034-6

0 references

Negative selection--clearing out the bad apples from the T-cell repertoire

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Simultaneous detection of circulating autoreactive CD8+ T-cells specific for different islet cell-associated epitopes using combinatorial MHC multimers.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Discovery of low-affinity preproinsulin epitopes and detection of autoreactive CD8 T-cells using combinatorial MHC multimers.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Projection of an immunological self shadow within the thymus by the aire protein

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

CD8 T cell autoreactivity to preproinsulin epitopes with very low human leucocyte antigen class I binding affinity.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

The islet-specific glucose-6-phosphatase-related protein, implicated in diabetes, is a glycoprotein embedded in the endoplasmic reticulum membrane.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP)

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Alternative splicing of G6PC2, the gene coding for the islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP), results in differential expression in human thymus and spleen compared with pancreas

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

IA-2-autoantibodies complement GAD65-autoantibodies in new-onset IDDM patients and help predict impending diabetes in their siblings. The Belgian Diabetes Registry

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Clonal deletion and the fate of autoreactive thymocytes that survive negative selection

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Low-affinity major histocompatibility complex-binding peptides in type 1 diabetes.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Mechanisms maintaining peripheral tolerance.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Deletional tolerance mediated by extrathymic Aire-expressing cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Autoantigen recognition is required for recruitment of IGRP(206-214)-autoreactive CD8+ T cells but is dispensable for tolerance.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3034-6

21 January 2018

CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24030068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in the cellular composition of the thymus in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/24030068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel, highly efficient peptide-HLA class I binding assay using unfolded heavy chain molecules: identification of HIV-1 derived peptides that bind to HLA-A*0201 and HLA-A*0301

1 reference

https://pubmed.ncbi.nlm.nih.gov/24030068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of CD4+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: a novel beta cell autoantigen in type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24030068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-013-3034-6

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

ResearchGate publication ID

0 references

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