(Q44473943)

3 December 2017

title

Increased insulin clearance in peroxisome proliferator-activated receptor gamma2 Pro12Ala (English)

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3 December 2017

3

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3 December 2017

12

Michael Stumvoll

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3 December 2017

2

Andreas Fritsche

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3 December 2017

10

Fausto Machicao

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3 December 2017

5

Claus Thamer

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3 December 2017

4

Michael Haap

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3 December 2017

11

Hans Häring

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3 December 2017

7

Dominik Dahl

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3 December 2017

1

Otto Tschritter

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3 December 2017

8

Elke Maerker

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3 December 2017

9

Anna Teigeler

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3 December 2017

6

Oliver Bachmann

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3 December 2017

publication date

1 June 2003

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3 December 2017

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3 December 2017

volume

52

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3 December 2017

issue

6

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3 December 2017

page(s)

778-783

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Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation

3 December 2017

cites work

1 reference

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The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

7 January 2021

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The Pro12 -->Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes

7 January 2021

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PPARgamma, the ultimate thrifty gene

7 January 2021

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Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations

7 January 2021

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A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

The PPARgamma2 amino acid polymorphism Pro 12 Ala is prevalent in offspring of Type II diabetic patients and is associated to increased insulin sensitivity in a subgroup of obese subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

A genetic polymorphism of the peroxisome proliferator-activated receptor gamma gene influences plasma leptin levels in obese humans

7 January 2021

1 reference

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Effect of the Pro12Ala variant of the human peroxisome proliferator-activated receptor gamma 2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

The PPARgamma2 polymorphism pro12Ala is associated with better insulin sensitivity in the offspring of type 2 diabetic patients.

7 January 2021

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CEACAM1 regulates insulin clearance in liver

7 January 2021

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Polymorphism of pro12Ala in peroxisome proliferator activated receptor gamma 2 (PPAgamma2): beta cell function and insulin sensitivity

7 January 2021

1 reference

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Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene

7 January 2021

1 reference

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Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma2 gene is associated with increased antilipolytic insulin sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

Interaction effect between common polymorphisms in PPARgamma2 (Pro12Ala) and insulin receptor substrate 1 (Gly972Arg) on insulin sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

A novel hyperglycaemic clamp for characterization of islet function in humans: assessment of three different secretagogues, maximal insulin response and reproducibility.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

Independent influence of age on basal insulin secretion in nondiabetic humans. European Group for the Study of Insulin Resistance

7 January 2021

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Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response

7 January 2021

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Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

7 January 2021

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Insulin sensitivity of suppression of endogenous glucose production is the single most important determinant of glucose tolerance

7 January 2021

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Role of fatty acids in the pathogenesis of insulin resistance and NIDDM.

7 January 2021

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Free-fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

Fatty acids in the portal vein of the rat regulate hepatic insulin clearance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

Free fatty acids impair hepatic insulin extraction in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

Alterations in the glucose-stimulated insulin secretory dose-response curve and in insulin clearance in nondiabetic insulin-resistant individuals.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

Splanchnic insulin metabolism in obesity. Influence of body fat distribution

7 January 2021

1 reference

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Reduced Hepatic Insulin Extraction in Obesity: Relationship with Plasma Insulin Levels

7 January 2021

1 reference

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Non-esterified fatty acids and the liver: why is insulin secreted into the portal vein?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin

7 January 2021

1 reference

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Free Fatty Acid as a Link in the Regulation of Hepatic Glucose Output by Peripheral Insulin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

The effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

The limitations to and valid use of C-peptide as a marker of the secretion of insulin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

C-Peptide as a Measure of the Secretion and Hepatic Extraction of Insulin: Pitfalls and Limitations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0026-0495%2803%2900071-4

10.1016/S0026-0495(03)00071-4

7 January 2021

Identifiers

DOI

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3 December 2017

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