(Q44540460)

4 December 2017

title

Catalysis by RNase P RNA: unique features and unprecedented active site plasticity (English)

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4 December 2017

Tina Persson

1

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4 December 2017

Simona Cuzic

series ordinal

2

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4 December 2017

Roland K Hartmann

series ordinal

3

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4 December 2017

language of work or name

English

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publication date

6 August 2003

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Journal of Biological Chemistry

4 December 2017

number of pages

8

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based on heuristic

inferred from page(s)

published in

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4 December 2017

volume

278

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4 December 2017

issue

44

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4 December 2017

page(s)

43394-43401

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Ribonuclease P: unity and diversity in a tRNA processing ribozyme

4 December 2017

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1 reference

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Ribonuclease P (RNase P) RNA is converted to a Cd(2+)-ribozyme by a single Rp-phosphorothioate modification in the precursor tRNA at the RNase P cleavage site

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The residue immediately upstream of the RNase P cleavage site is a positive determinant

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Evidence for a polynuclear metal ion binding site in the catalytic domain of ribonuclease P RNA.

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External Guide Sequences for an RNA Enzyme

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Important 2'-hydroxyl groups in model substrates for M1 RNA, the catalytic RNA subunit of RNase P from Escherichia coli

21 January 2018

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Pathway of Activation by Magnesium Ions of Substrates for the Catalytic Subunit of RNase P from Escherichia coli

21 January 2018

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NMR spectroscopic evidence for Mn(2+)(Mg(2+)) binding to a precursor-tRNA microhelix near the potential RNase P cleavage site

21 January 2018

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Selection of hammerhead ribozyme variants with low Mg2+ requirement: importance of stem-loop II.

21 January 2018

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Differential role of the intermolecular base-pairs G292-C(75) and G293-C(74) in the reaction catalyzed by Escherichia coli RNase P RNA.

21 January 2018

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Exploring the minimal substrate requirements for trans-cleavage by RNase P holoenzymes from Escherichia coli and Bacillus subtilis

21 January 2018

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Guanosine 2-NH2 groups of Escherichia coli RNase P RNA involved in intramolecular tertiary contacts and direct interactions with tRNA.

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21 January 2018

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The protein component of Bacillus subtilis ribonuclease P increases catalytic efficiency by enhancing interactions with the 5' leader sequence of pre-tRNAAsp

21 January 2018

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The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction

21 January 2018

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The role of the cleavage site 2'-hydroxyl in the Tetrahymena group I ribozyme reaction

21 January 2018

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Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability

21 January 2018

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21 January 2018

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Solution structure of the A loop of 23S ribosomal RNA

21 January 2018

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A physical assay for and kinetic analysis of the interactions between M1 RNA and tRNA precursor substrates.

21 January 2018

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The additional guanylate at the 5' terminus of Escherichia coli tRNAHis is the result of unusual processing by RNase P.

21 January 2018

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The unusually long amino acid acceptor stem of Escherichia coli selenocysteine tRNA results from abnormal cleavage by RNase P.

21 January 2018

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Different cleavage sites are aligned differently in the active site of M1 RNA, the catalytic subunit of Escherichia coli RNase P.

21 January 2018

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Recognition of the 5' leader of pre-tRNA substrates by the active site of ribonuclease P.

21 January 2018

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Ribonuclease P catalysis requires Mg2+ coordinated to the pro-RP oxygen of the scissile bond.

21 January 2018

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Structural and catalytic roles for divalent magnesium in nucleic acid biochemistry

21 January 2018

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Active site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3'-S-phosphorothiolate internucleotide linkage

21 January 2018

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Multiple magnesium ions in the ribonuclease P reaction mechanism

21 January 2018

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Role of metal ions in the hydrolysis reaction catalyzed by RNase P RNA from Bacillus subtilis

21 January 2018

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The affinity of magnesium binding sites in the Bacillus subtilis RNase P x pre-tRNA complex is enhanced by the protein subunit

21 January 2018

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A kinetic mechanism for cleavage of precursor tRNA(Asp) catalyzed by the RNA component of Bacillus subtilis ribonuclease P

21 January 2018

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Recognition of the T stem-loop of a pre-tRNA substrate by the ribozyme from Bacillus subtilis ribonuclease P

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305939200

Manganese ions induce miscleavage in the Escherichia coli RNase P RNA-catalyzed reaction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305939200

Importance of the +73/294 interaction in Escherichia coli RNase P RNA substrate complexes for cleavage and metal ion coordination

21 January 2018

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A hydrogen-bonding triad stabilizes the chemical transition state of a group I ribozyme

21 January 2018

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Synthesis and Properties of Diuridine Phosphate Analogues Containing Thio and Amino Modifications

21 January 2018

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Identification of individual nucleotides in the bacterial ribonuclease P ribozyme adjacent to the pre-tRNA cleavage site by short-range photo-cross-linking

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M305939200

1 reference

4 December 2017

1 reference