(Q44552387)

4 December 2017

Transactivation joins multiple tracks to the ERK/MAPK cascade (English)

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4 December 2017

Reinhard Wetzker

1

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PubMed ID

12923527

4 December 2017

Frank-D Böhmer

series ordinal

2

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4 December 2017

1 August 2003

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Nature Reviews Molecular Cell Biology

4 December 2017

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4 December 2017

4

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4 December 2017

8

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4 December 2017

651-657

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https://scigraph.springernature.com/pub.10.1038/nrm1173

4 December 2017

0 references

cites work

Cell signaling by receptor tyrosine kinases

1 reference

Seven-transmembrane receptors

31 March 2020

1 reference

EGF receptor phosphorylation is affected by ionizing radiation

31 March 2020

1 reference

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

31 March 2020

1 reference

Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.

31 March 2020

1 reference

Ras-MAP kinase signaling by lysophosphatidic acid and other G protein-coupled receptor agonists

31 March 2020

1 reference

New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

31 March 2020

1 reference

Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission

31 March 2020

1 reference

Integration of signals from receptor tyrosine kinases and g protein-coupled receptors.

31 March 2020

1 reference

EGF receptor transactivation mediated by the proteolytic production of EGF-like agonists

31 March 2020

1 reference

Signal characteristics of G protein-transactivated EGF receptor

31 March 2020

1 reference

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy

31 March 2020

1 reference

Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

31 March 2020

1 reference

Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding

31 March 2020

1 reference

Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation

31 March 2020

1 reference

Helicobacter pylori-stimulated EGF receptor transactivation requires metalloprotease cleavage of HB-EGF.

31 March 2020

1 reference

Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced ce

31 March 2020

1 reference

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

31 March 2020

1 reference

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

31 March 2020

1 reference

c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

31 March 2020

1 reference

Carbachol-stimulated transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T(84) cells is mediated by intracellular Ca2+, PYK-2, and p60(src).

31 March 2020

1 reference

New members of the platelet-derived growth factor family of mitogens

31 March 2020

1 reference

Thrombin Stimulates Phosphorylation of Insulin-like Growth Factor-1 Receptor, Insulin Receptor Substrate-1, and Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells

31 March 2020

1 reference

Activation of Trk neurotrophin receptors in the absence of neurotrophins

31 March 2020

1 reference

Integrative nuclear FGFR1 signaling (INFS) pathway mediates activation of the tyrosine hydroxylase gene by angiotensin II, depolarization and protein kinase C.

31 March 2020

1 reference

Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases

31 March 2020

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Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo

31 March 2020

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Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

31 March 2020

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Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation

31 March 2020

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Participation of reactive oxygen species in the lysophosphatidic acid-stimulated mitogen-activated protein kinase kinase activation pathway

31 March 2020

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Stimulation of a vascular smooth muscle cell NAD(P)H oxidase by thrombin. Evidence that p47(phox) may participate in forming this oxidase in vitro and in vivo

31 March 2020

1 reference

Regulation of MAP kinase activity by peptide receptor signalling pathway: paradigms of multiplicity

31 March 2020

1 reference

Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

31 March 2020

1 reference

beta 2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein rap1 and the serine/threonine kinase B-Raf

31 March 2020

1 reference

Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade

31 March 2020

1 reference

A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid.

31 March 2020

1 reference

Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

31 March 2020

1 reference

Bradykinin B(2) receptor-mediated mitogen-activated protein kinase activation in COS-7 cells requires dual signaling via both protein kinase C pathway and epidermal growth factor receptor transactivation

31 March 2020

1 reference

Protease-activated receptor-1-mediated DNA synthesis in cardiac fibroblast is via epidermal growth factor receptor transactivation: distinct PAR-1 signaling pathways in cardiac fibroblasts and cardiomyocytes

31 March 2020

1 reference

Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling

31 March 2020

1 reference

Cross talk between beta-adrenergic and bradykinin B(2) receptors results in cooperative regulation of cyclic AMP accumulation and mitogen-activated protein kinase activity

31 March 2020

1 reference

Mechanisms of protease-activated receptor-4 actions in cardiomyocytes. Role of Src tyrosine kinase

31 March 2020

1 reference

Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant.

31 March 2020

1 reference

Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

31 March 2020

1 reference

A permissive function of phosphoinositide 3-kinase in Ras activation mediated by inhibition of GTPase-activating proteins

31 March 2020

1 reference

Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C. Signal amplification at the level of Raf by activation of protein kinase Cepsilon

31 March 2020

1 reference

Rapid transactivation of the vascular endothelial growth factor receptor KDR/Flk-1 by the bradykinin B2 receptor contributes to endothelial nitric-oxide synthase activation in cardiac capillary endothelial cells

31 March 2020

1 reference

Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor

31 March 2020

1 reference

Critical role of calcium- dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling

31 March 2020

1 reference

Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival

31 March 2020

1 reference

Transactivation of the epidermal growth factor receptor is involved in 12-O-tetradecanoylphorbol-13-acetate-induced signal transduction

31 March 2020

1 reference

G-protein coupled and tyrosine kinase receptors: evidence that activation of the insulin-like growth factor I receptor is required for thrombin-induced mitogenesis of rat aortic smooth muscle cells

31 March 2020

1 reference

Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells

31 March 2020

1 reference

Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells

31 March 2020

1 reference

The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptors

31 March 2020

1 reference

Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells

31 March 2020

1 reference

TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells

31 March 2020

1 reference

Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate

31 March 2020

1 reference

Oxidation state of the active-site cysteine in protein tyrosine phosphatase 1B

31 March 2020

1 reference

https://api.fatcat.wiki/v0/release/v5keadid7rfpjdpsnkrn3s324u

31 March 2020

Identifiers

1 reference

mapped directly with Wikidata item

30 July 2022

based on heuristic

Fatcat ID

release_v5keadid7rfpjdpsnkrn3s324u

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/v5keadid7rfpjdpsnkrn3s324u

mapped directly with Wikidata item

30 July 2022

based on heuristic

1 reference

https://api.fatcat.wiki/v0/release/v5keadid7rfpjdpsnkrn3s324u