(Q44571675)

English

Epidermal growth factor receptor-dependent, NF-kappaB-independent activation of the phosphatidylinositol 3-kinase/Akt pathway inhibits ultraviolet irradiation-induced caspases-3, -8, and -9 in human keratinocytes

scientific article published on 2 September 2003

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Epidermal growth factor receptor-dependent, NF-kappaB-independent activation of the phosphatidylinositol 3-kinase/Akt pathway inhibits ultraviolet irradiation-induced caspases-3, -8, and -9 in human keratinocytes (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

ultraviolet radiation

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Hui Qin Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Taihao Quan

2

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Tianyuan He

3

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Thomas F Franke

4

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

John J Voorhees

5

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Gary J Fisher

6

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

language of work or name

0 references

publication date

2 September 2003

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

46

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

45737-45745

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Molecular mechanisms of UV-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

PI3-kinase inhibition: a target for drug development?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

alpha5beta1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

IAP family proteins--suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Akt is a downstream target of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

The I kappa B kinase: a master regulator of NF-kappa B, innate immunity, and epidermal differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

NF-kappaB determines localization and features of cell death in epidermis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Signaling by distinct classes of phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

The role of c-FLIP in modulation of CD95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Interferon alpha /beta promotes cell survival by activating nuclear factor kappa B through phosphatidylinositol 3-kinase and Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Sunburn and p53 in the onset of skin cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Fas/Fas ligand interaction contributes to UV-induced apoptosis in human keratinocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Insulin-mediated stimulation of protein kinase Akt: A potent survival signaling cascade for endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

UVB-induced epidermal growth factor receptor phosphorylation is critical for downstream signaling and keratinocyte survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Differential expression of protein kinase C isoenzymes in normal and psoriatic adult human skin: reduced expression of protein kinase C-beta II in psoriasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Fas ligand: a sensor for DNA damage critical in skin cancer etiology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Activation of caspase-9 is required for UV-induced apoptosis of human keratinocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300574200

21 January 2018

Identifiers

10.1074/JBC.M300574200

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44571675&oldid=2028459703"