(Q44573728)

English

Synthesis of potent beta-secretase inhibitors containing a hydroxyethylamine dipeptide isostere and their structure-activity relationship studies

scientific article published in July 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 December 2017

Synthesis of potent beta-secretase inhibitors containing a hydroxyethylamine dipeptide isostere and their structure-activity relationship studies (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Hirokazu Tamamura

1

object named as

Hirokazu Tamamura

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

author name string

Terukazu Kato

2

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Akira Otaka

3

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Nobutaka Fujii

4

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

publication date

1 July 2003

1 reference

Europe PubMed Central

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4 December 2017

Organic and Biomolecular Chemistry

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Europe PubMed Central

PubMed publication ID

4 December 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

2468-2473

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Translating cell biology into therapeutic advances in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Cellular mechanisms of beta-amyloid production and secretion

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Purification and cloning of amyloid precursor protein beta-secretase from human brain

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Hydroxyethylamine analogues of the p17/p24 substrate cleavage site are tight-binding inhibitors of HIV protease

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Rational design of peptide-based HIV proteinase inhibitors

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Potent HIV protease inhibitors incorporating high-affinity P2-ligands and (R)-(hydroxyethylamino)sulfonamide isostere

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Reduction of Peptide Character of HIV Protease Inhibitors That Exhibit Nanomolar Potency against Multidrug Resistant HIV-1 Strains

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Design of substrate-based inhibitors of human beta-secretase

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Structure-based design: potent inhibitors of human brain memapsin 2 (beta-secretase).

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Crystal structure of memapsin 2 (beta-secretase) in complex with an inhibitor OM00-3

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Subsite specificity of memapsin 2 (beta-secretase): implications for inhibitor design.

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Combinatorial solid-phase synthesis of balanol analogues

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Design of Potent Inhibitors for Human Brain Memapsin 2 (β-Secretase)

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Orally active water-soluble N,O-acyl transfer products of a beta,gamma-bishydroxyl amide containing renin inhibitor

1 reference

https://api.crossref.org/works/10.1039%2FB304842J

21 January 2018

Identifiers

10.1039/B304842J

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

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