(Q44588841)

4 December 2017

Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway (English)

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4 December 2017

Jie Zhang

1

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4 December 2017

Yong Choi

2

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4 December 2017

Blanche Mavromatis

3

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4 December 2017

Alan Lichtenstein

4

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4 December 2017

Weiqun Li

5

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4 December 2017

language of work or name

English

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publication date

1 September 2003

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4 December 2017

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4 December 2017

22

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4 December 2017

6289-6295

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4 December 2017

40

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206718

4 December 2017

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cites work

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

Recent advances in the treatment of multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

Cytogenetics and molecular genetics in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

Myeloma biology and therapy. Present status and future developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

PKB/AKT: functional insights from genetic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

PTEN: life as a tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

Mechanism of activation of protein kinase B by insulin and IGF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Expression of PTEN in PTEN-deficient multiple myeloma cells abolishes tumor growth in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

The AKT kinase is activated in multiple myeloma tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Role of the AKT kinase in expansion of multiple myeloma clones: effects on cytokine-dependent proliferative and survival responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Mechanisms of myeloma cell growth control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Update on the treatment of multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Protein kinase C-delta is an important signaling molecule in insulin-like growth factor I receptor-mediated cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Protein kinase C-alpha overexpression stimulates Akt activity and suppresses apoptosis induced by interleukin 3 withdrawal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Biology and treatment of multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Signalling through the lipid products of phosphoinositide-3-OH kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206718

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206718

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4 December 2017

1 reference