(Q44624759)

4 December 2017

title

Low dose genotoxicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in gpt delta transgenic mice (English)

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4 December 2017

1 reference

1 reference

https://api.crossref.org/works/10.1016/S1383-5718(03)00186-4

23 March 2024

1

Ken-ichi Masumura

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14568298

23 March 2024

author name string

Mieko Horiguchi

2

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4 December 2017

Akiyoshi Nishikawa

3

1 reference

4 December 2017

Takashi Umemura

4

1 reference

4 December 2017

Keita Kanki

5

1 reference

4 December 2017

Yusuke Kanke

6

1 reference

4 December 2017

Takehiko Nohmi

7

1 reference

4 December 2017

language of work or name

English

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publication date

1 November 2003

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4 December 2017

10 November 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14568298

full work available at URL

23 March 2024

https://api.elsevier.com/content/article/PII:S1383571803001864?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S1383-5718(03)00186-4

https://api.elsevier.com/content/article/PII:S1383571803001864?httpAccept=text/plain

23 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1383-5718(03)00186-4

23 March 2024

1 reference

4 December 2017

volume

541

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4 December 2017

issue

1-2

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4 December 2017

page(s)

91-102

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DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis

4 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Carcinogenicity in rats of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Carcinogenicity in mice of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) from cooked foods

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Induction of aberrant crypt foci in C57BL/6N mice by 2-amino-9H-pyrido[2,3-b]indole (A alphaC) and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

N-hydroxy-MeIQx is the major microsomal oxidation product of the dietary carcinogen MeIQx with human liver

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Metabolism of the food-borne mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Metabolic activation of the N-hydroxy derivative of the carcinogen 4-aminobiphenyl by human tissue sulfotransferases.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Direct O-acetylation of N-hydroxy arylamines by acetylsalicylic acid to form carcinogen-DNA adducts

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

32P-postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx- and PhIP-treated monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Identification of N2-(deoxyguanosin-8-yl)-2-amino-3,8-dimethyl-imidazo[4,5- f]quinoxaline 3',5'-diphosphate, a major DNA adduct, detected by nuclease P1 modification of the 32P-postlabeling method, in the liver of rats fed MeIQx

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Presence of carcinogenic heterocyclic amines in urine of healthy volunteers eating normal diet, but not of inpatients receiving parenteral alimentation.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Estimation of dietary HCA intakes in a large-scale population-based prospective study in Japan

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Thresholds in genetic toxicology - concluding remarks

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Concepts of threshold in mutagenesis and carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Recent advances in the protocols of transgenic mouse mutation assays.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Mutagenicity of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) in the new gpt delta transgenic mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Spectra of gpt mutations in ethylnitrosourea-treated and untreated transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Characterization of mutations induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the colon of gpt delta transgenic mouse: novel G:C deletions beside runs of identical bases

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Further characterization and validation of gpt delta transgenic mice for quantifying somatic mutations in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Spi(-) selection: An efficient method to detect gamma-ray-induced deletions in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Heavy-ion-induced mutations in the gpt delta transgenic mouse: comparison of mutation spectra induced by heavy-ion, X-ray, and gamma-ray radiation.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Molecular characterization of mitomycin C-induced large deletions and tandem-base substitutions in the bone marrow of gpt delta transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Statistical test for the comparison of samples from mutational spectra

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Computer program for the analysis of mutational spectra: application to p53 mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Low-dose carcinogenicity of a heterocyclic amine, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline: relevance to risk assessment.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Dose-response study of MeIQx carcinogenicity in F344 male rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Genetic analysis of PHIP intestinal mutations in MutaMouse

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Agreement of mutational characteristics of heterocyclic amines in lacI of the Big Blue mouse with those in tumor related genes in rodents.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Mutagenesis of the N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine DNA adduct in mammalian cells. Sequence context effects

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Mutational analysis of the liver, colon and kidney of Big Blue rats treated with 2-amino-3-methylimidazo[4,5-f]quinoline.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Novel DNA polymerases offer clues to the molecular basis of mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Proliferation is necessary for both repair and mutation in transgenic mouse cells

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Does oxidative damage to DNA increase with age?

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2803%2900186-4

7 January 2021

Molecular nature of ultraviolet B light-induced deletions in the murine epidermis

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1 reference

https://api.crossref.org/works/10.1016/S1383-5718(03)00186-4

23 March 2024

Identifiers

1 reference

4 December 2017

1 reference