(Q44645110)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14602090%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

Cyclothiazide binding to functionally active AMPA receptor reveals genuine allosteric interaction with agonist binding sites (English)

1 reference

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20 December 2019

5

1 reference

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20 December 2019

Agnes Simon

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14602090%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

author name string

Ilona Kovács

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14602090%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Eva Szárics

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14602090%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Péter Barabás

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14602090%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Lajos Nyikos

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14602090%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Julianna Kardos

7

1 reference

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20 December 2019

publication date

1 March 2004

1 reference

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Neurochemistry International

20 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14602090%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

volume

44

1 reference

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20 December 2019

issue

4

1 reference

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20 December 2019

page(s)

271-280

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14602090%20AND%20SRC:MED&resulttype=core&format=json

Effects of the potent ampakine CX614 on hippocampal and recombinant AMPA receptors: interactions with cyclothiazide and GYKI 52466

20 December 2019

cites work

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7 January 2021

Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

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7 January 2021

Structure of a glutamate-receptor ligand-binding core in complex with kainate

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7 January 2021

Hydrogen bonding in globular proteins

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7 January 2021

Validation of the general purpose Tripos 5.2 force field

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7 January 2021

Activation kinetics of AMPA receptor channels reveal the number of functional agonist binding sites.

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7 January 2021

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

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7 January 2021

Pharmacology and regional distribution of the binding of 6-[3H]nitro-7-sulphamoylbenzo[f]-quinoxaline-2,3-dione to rat brain

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7 January 2021

A new model for calculating atomic charges in molecules

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7 January 2021

Cyclothiazide decreases [3H]AMPA binding to rat brain membranes: evidence that AMPA receptor desensitization increases agonist affinity.

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7 January 2021

Characterization of the pharmacology and regional distribution of (S)-[3H]-5-fluorowillardiine binding in rat brain

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7 January 2021

Binding of the new radioligand (S)-[3H]AMPA to rat brain synaptic membranes: effects of a series of structural analogues of the non-NMDA receptor agonist willardiine

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7 January 2021

Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal

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7 January 2021

Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate

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7 January 2021

Transmembrane 36Cl- flux measurements and desensitization of the gamma-aminobutyric acidA receptor

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7 January 2021

Universality of receptor channel responses

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7 January 2021

Modulation of GABA flux across rat brain membranes resolved by a rapid quenched incubation technique.

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7 January 2021

Regulation of kinetic properties of GluR2 AMPA receptor channels by alternative splicing.

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7 January 2021

Glutamic acid agonists. Stereochemical and conformational studies of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and related compounds

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7 January 2021

Binding of an AMPA receptor potentiator ([3H]LY395153) to native and recombinant AMPA receptors

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7 January 2021

DNQX-induced toxicity in cultured rat hippocampal neurons: an apparent AMPA receptor-independent effect?

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7 January 2021

Satisfying hydrogen bonding potential in proteins

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7 January 2021

A molecular determinant for submillisecond desensitization in glutamate receptors

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7 January 2021

Ligand-specific conformations of an ionotropic glutamate receptor

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7 January 2021

Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A.

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7 January 2021

AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracetam, and thiocyanate.

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7 January 2021

Evidence for a role of presynaptic AMPA receptors in the control of neuronal glutamate release in the rat forebrain.

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7 January 2021

Subunit interactions and AMPA receptor desensitization.

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7 January 2021

Ion channels: how to be desensitized

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7 January 2021

The tetrameric structure of a glutamate receptor channel

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7 January 2021

First images of a glutamate receptor ion channel: oligomeric state and molecular dimensions of GluRB homomers

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7 January 2021

Modeling MHC class II molecules and their bound peptides as expressed at the cell surface

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7 January 2021

Inherent desensitisation-preventing properties of a novel, subtype-selective AMPA receptor agonist, (S)-CPW 399, as a possible explanation for its excitotoxic action in cultured cerebellar granule cells

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7 January 2021

Heterogeneous conductance levels of native AMPA receptors

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7 January 2021

Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

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7 January 2021

Mechanism of glutamate receptor desensitization

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7 January 2021

Kinetically distinguishable AMPA receptors in rat hippocampus are associated with the loss of glutamate-sensitive conformational transitions

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7 January 2021

Quinazolone-alkyl-carboxylic acid derivatives inhibit transmembrane Ca(2+) ion flux to (+)-(S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid

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7 January 2021

Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents.

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7 January 2021