(Q44658072)

5 December 2017

title

Activated Notch1 associates with a presenilin-1/gamma-secretase docking site (English)

1 reference

5 December 2017

Activated Notch1 associates with a presenilin‐1/γ‐secretase docking site (English)

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

2 April 2024

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

2 April 2024

4

Bradley T Hyman

1 reference

5 December 2017

1

Pavan Ramdya

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622115

2 April 2024

2

Jesse Skoch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622115

2 April 2024

author name string

Oksana Berezovska

5

1 reference

5 December 2017

Brian J. Bacskai

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622115

2 April 2024

Bradley T. Hyman

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622115

2 April 2024

language of work or name

English

0 references

publication date

1 November 2003

1 reference

full work available at URL

5 December 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1471-4159.2003.02030.x

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1471-4159.2003.02030.x

2 April 2024

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Journal of Neurochemistry

2 April 2024

published in

1 reference

5 December 2017

volume

87

1 reference

5 December 2017

issue

4

1 reference

5 December 2017

page(s)

843-850

1 reference

Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2

5 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2003.02030.X

What do we learn from a few familial Alzheimer's disease cases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2003.02030.X

Notch signaling: cell fate control and signal integration in development

21 January 2018

1

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Muscarinic agonists induce phosphorylation-independent activation of the NHE-1 isoform of the Na+/H+ antiporter in salivary acinar cells

2 April 2024

2

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Fluorescence resonance energy transfer determinations using multiphoton fluorescence lifetime imaging microscopy to characterize amyloid-beta plaques

2 April 2024

3

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

The Alzheimer-related gene presenilin 1 facilitates notch 1 in primary mammalian neurons.

2 April 2024

4

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Rapid Notch1 nuclear translocation after ligand binding depends on presenilin-associated gamma-secretase activity

2 April 2024

5

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging.

2 April 2024

6

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein

2 April 2024

8

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

2 April 2024

9

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.

2 April 2024

10

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate

2 April 2024

11

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Notch and presenilin: a proteolytic mechanism emerges

2 April 2024

12

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

2 April 2024

13

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos

2 April 2024

14

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Nectin-1alpha, an immunoglobulin-like receptor involved in the formation of synapses, is a substrate for presenilin/gamma-secretase-like cleavage

2 April 2024

17

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s).

2 April 2024

18

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

2 April 2024

19

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

2 April 2024

20

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

2 April 2024

21

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Constitutively active human Notch1 binds to the transcription factor CBF1 and stimulates transcription through a promoter containing a CBF1-responsive element

2 April 2024

22

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

2 April 2024

23

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

2 April 2024

24

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch

2 April 2024

25

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Evidence for a physical interaction between presenilin and Notch

2 April 2024

26

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Presenilin-1 and -2 are molecular targets for gamma-secretase inhibitors

2 April 2024

28

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

2 April 2024

29

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors

2 April 2024

30

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Presenilin is required for activity and nuclear access of Notch in Drosophila

2 April 2024

31

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Linear non-competitive inhibition of solubilized human gamma-secretase by pepstatin A methylester, L685458, sulfonamides, and benzodiazepines

2 April 2024

32

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

2 April 2024

34

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

2 April 2024

35

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02030.X

2 April 2024

Identifiers

1 reference

5 December 2017

1 reference