(Q44688680)

5 December 2017

Wogonin induced cytotoxicity in human hepatocellular carcinoma cells by activation of unfolded protein response and inactivation of AKT. (English)

1 reference

5 December 2017

hepatocellular carcinoma

1 reference

1 reference

Min Xu

1

1 reference

5 December 2017

Na Lu

2

1 reference

5 December 2017

Haiwei Zhang

3

1 reference

5 December 2017

Qinsheng Dai

4

1 reference

5 December 2017

Libin Wei

5

1 reference

5 December 2017

Zhiyu Li

6

1 reference

5 December 2017

Qidong You

7

1 reference

5 December 2017

Qinglong Guo

8

1 reference

5 December 2017

7 January 2013

1 reference

5 December 2017

1 reference

5 December 2017

43

1 reference

5 December 2017

8

1 reference

5 December 2017

890-905

1 reference

5 December 2017

Global cancer statistics

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

21 January 2018

Hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Major achievements in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

The role of signaling pathways in the development and treatment of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

21 January 2018

Hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Molecular mechanisms of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

The contribution of endoplasmic reticulum stress to liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Endoplasmic reticulum stress in liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

ER stress: can the liver cope?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Endoplasmic reticulum stress: cell life and death decisions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Signal integration in the endoplasmic reticulum unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

The critical role of GRP78 in physiologic and pathologic stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Integrated endoplasmic reticulum stress responses in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

GRP78 induction in cancer: therapeutic and prognostic implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Mediators of endoplasmic reticulum stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Coupling endoplasmic reticulum stress to the cell death program

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Targeting the PI3K-Akt pathway in human cancer: rationale and promise

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Exploiting the PI3K/AKT pathway for cancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Cancer chemoprevention with dietary phytochemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCdelta phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Anti-hepatitis B virus activity of wogonin in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Wogonin ameliorates lipotoxicity-induced apoptosis of cultured vascular smooth muscle cells via interfering with DAG-PKC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

The role of the unfolded protein response in tumour development: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Activation of the unfolded protein response contributed to the selective cytotoxicity of oroxylin A in human hepatocellular carcinoma HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Different apoptotic effects of wogonin via induction of H(2)O(2) generation and Ca(2+) overload in malignant hepatoma and normal hepatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Roles of CHOP/GADD153 in endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Wogonin potentiates the antitumor effects of low dose 5-fluorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

The anticancer activities of wogonin in murine sarcoma S180 both in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

The mitochondrion: is it central to apoptosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

IRE1 signaling affects cell fate during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Human TRB3 is upregulated in stressed cells by the induction of translationally efficient mRNA containing a truncated 5'-UTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Flavonoids: antioxidants or signalling molecules?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

Flavonoids as protein kinase inhibitors for cancer chemoprevention: direct binding and molecular modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FHEPR.12036

21 January 2018

Identifiers

DOI

10.1111/HEPR.12036

1 reference

release_czmzhm4qzfeatbdvtrtt4vumya

5 December 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/czmzhm4qzfeatbdvtrtt4vumya

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference