(Q44728737)

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Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability.

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 December 2017

Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

Alzheimer's disease

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author name string

Grace E Stutzmann

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

Antonella Caccamo

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

Frank M LaFerla

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

Ian Parker

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

language of work or name

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publication date

1 January 2004

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Journal of Neuroscience

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

24

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

508-513

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular distribution of the calcium-binding proteins parvalbumin, calbindin, and calretinin in the neocortex of mammals: phylogenetic and developmental patterns

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional phenotype in transgenic mice expressing mutant human presenilin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1,4,5-trisphosphate receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin-mediated modulation of capacitative calcium entry

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin-1 regulates the neuronal threshold to excitotoxicity both physiologically and pathologically

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local calcium release in dendritic spines required for long-term synaptic depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium stores regulate the polarity and input specificity of synaptic modification

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of Ca(2+)-dependent transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construction of a two-photon microscope for video-rate Ca(2+) imaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of cellular calcium homeostasis in Alzheimer's disease: bad genes and bad habits

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+) dynamics in the lumen of the endoplasmic reticulum in sensory neurons: direct visualization of Ca(2+)-induced Ca(2+) release triggered by physiological Ca(2+) entry

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A distinct form of calcium release down-regulates membrane excitability in neocortical pyramidal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related and laminar-specific dendritic changes in the medial frontal cortex of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endoplasmic reticulum: a multifunctional signaling organelle

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium leak from intracellular stores--the enigma of calcium signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ signaling in mouse cortical neurons studied by two-photon imaging and photoreleased inositol triphosphate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereologic analysis of neurofibrillary tangle formation in prefrontal cortex area 9 in aging and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of membrane currents evoked by photoreleased inositol trisphosphate in Xenopus oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+)-induced Ca2+ release and its activation in response to a single action potential in rabbit otic ganglion cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal Ca2+ stores: activation and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular basis of working memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium hypothesis of Alzheimer's disease and brain aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations of the presenilin I gene in families with early-onset Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+)-activated K+ currents in neurones: types, physiological roles and modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium responses in human fibroblasts: a diagnostic molecular profile for Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution of two calcium binding proteins, calbindin D-28K and parvalbumin, in the entorhinal cortex of the adult mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and molecular analysis of neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release and sequestration of calcium by ryanodine-sensitive stores in rat hippocampal neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective representation of relevant information by neurons in the primate prefrontal cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal calcium signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4386-03.2004

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729995&resulttype=core&format=json

12 May 2020

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