(Q44800009)

6 December 2017

title

The STAT3 isoforms alpha and beta have unique and specific functions (English)

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6 December 2017

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6 December 2017

9

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6 December 2017

Roberto Chiarle

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author name string

Diego Maritano

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6 December 2017

Michelle L Sugrue

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6 December 2017

Silvia Tininini

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6 December 2017

Sarah Dewilde

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6 December 2017

XinPing Fu

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6 December 2017

Victoria Murray-Tait

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6 December 2017

language of work or name

English

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publication date

14 March 2004

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6 December 2017

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6 December 2017

volume

5

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6 December 2017

issue

4

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6 December 2017

page(s)

401-409

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A road map for those who don't know JAK-STAT

6 December 2017

cites work

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The state of the STATs: recent developments in the study of signal transduction to the nucleus

21 January 2018

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Acute-Phase Response Factor, a Nuclear Factor Binding to Acute-Phase Response Elements, is Rapidly Activated by Interleukin-6 at the Posttranslational Level

21 January 2018

1 reference

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

21 January 2018

1 reference

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

21 January 2018

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The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family

21 January 2018

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21 January 2018

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 January 2018

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Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival.

21 January 2018

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A critical role for Stat3 signaling in immune tolerance

21 January 2018

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STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation

21 January 2018

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Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver

21 January 2018

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Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

21 January 2018

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Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice

21 January 2018

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Mutational switch of an IL-6 response to an interferon-gamma-like response

21 January 2018

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Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3

21 January 2018

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STAT3 contributes to the mitogenic response of hepatocytes during liver regeneration

21 January 2018

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SOCS3 regulates the plasticity of gp130 signaling

21 January 2018

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SOCS3 negatively regulates IL-6 signaling in vivo

21 January 2018

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IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

21 January 2018

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Functional differences between Stat3alpha and Stat3beta

21 January 2018

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Mutational analysis of acute-phase response factor/Stat3 activation and dimerization

21 January 2018

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STAT signaling is active during early mammalian development.

21 January 2018

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Stat protein transactivation domains recruit p300/CBP through widely divergent sequences

21 January 2018

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Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a

21 January 2018

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Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation

21 January 2018

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Functional importance of Stat3 tetramerization in activation of the alpha 2-macroglobulin gene

21 January 2018

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Synergistic activity of STAT3 and c-Jun at a specific array of DNA elements in the alpha 2-macroglobulin promoter

21 January 2018

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The SOCS box: a tale of destruction and degradation

21 January 2018

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Role of Stat3 in lipopolysaccharide-induced IL-10 gene expression.

21 January 2018

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IFN-alpha induces the human IL-10 gene by recruiting both IFN regulatory factor 1 and Stat3.

21 January 2018

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Soluble interleukin 6 receptor is biologically active in vivo

21 January 2018

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Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

21 January 2018

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Defective inflammatory response in interleukin 6-deficient mice

21 January 2018

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Analysis of Gene Expression Using High-Density and IFN-γ-Specific Low-Density cDNA Arrays

21 January 2018

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A completely foreign receptor can mediate an interferon-gamma-like response

21 January 2018

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STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription

21 January 2018

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7 January 2021

Specific ablation of Stat3beta distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock

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7 January 2021

Dimer stability as a determinant of differential DNA binding activity of Stat3 isoforms

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7 January 2021

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

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7 January 2021

Identifiers

DOI

10.1038/NI1052

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Dimensions Publication ID

6 December 2017

1015745019

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