(Q44898890)

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Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15147316%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice (English)

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28 December 2019

Alzheimer's disease

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7

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28 December 2019

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28 December 2019

Masaaki Matsuoka

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Masaaki Matsuoka

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28 December 2019

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Masaoki Kawasumi

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28 December 2019

Marina Yamada

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28 December 2019

Makiko Miyamae-Kaneko

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28 December 2019

Jin Nakahara

6

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28 December 2019

Takeshi Iwatsubo

8

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28 December 2019

Shigeaki Kato

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28 December 2019

Sadakazu Aiso

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28 December 2019

Ikuo Nishimoto

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28 December 2019

Keisuke Kouyama

12

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28 December 2019

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1 May 2004

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28 December 2019

European Journal of Neuroscience

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28 December 2019

19

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28 December 2019

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28 December 2019

2826-2838

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28 December 2019

Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies

1 reference

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21 January 2018

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

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21 January 2018

Beta A4 protein deposition in familial Alzheimer's disease with the mutation in codon 717 of the beta A4 amyloid precursor protein gene and sporadic Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Amyloidogenicity of rodent and human beta A4 sequences.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Vasopressin potentiation in the performance of a learned appetitive task: reversal by a pressor antagonist analog of vasopressin.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

FAD mutant PS-1 gene-targeted mice: increased A beta 42 and A beta deposition without APP overproduction

1 reference

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21 January 2018

Very old women at highest risk of dementia and Alzheimer's disease: incidence data from the Kungsholmen Project, Stockholm.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Expression of beta amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Multiple mechanisms underlie neurotoxicity by different types of Alzheimer's disease mutations of amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Annual incidence of Alzheimer disease in the United States projected to the years 2000 through 2050.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Estrogen replacement therapy in older women. Comparisons between Alzheimer's disease cases and nondemented control subjects

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Differential effects of pimozide and SCH 23390 on acquisition of learning in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Molecular and prospective phenotypic characterization of a pedigree with familial Alzheimer's disease and a missense mutation in codon 717 of the beta-amyloid precursor protein gene

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Molecular mechanisms for neuronal cell death by Alzheimer's amyloid precursor protein-relevant insults

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Latent learning in hippocampal-lesioned rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Further evidence for latent learning in hippocampal-lesioned rats.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Enhancement of spatial attention in nociceptin/orphanin FQ receptor-knockout mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Age-related changes in learning and memory in the senescence-accelerated mouse (SAM).

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Proline-directed and non-proline-directed phosphorylation of PHF-tau.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Beta-amyloid precursor polypeptide in SAMP8 mice affects learning and memory.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Effects of nefiracetam on drug-induced impairment of latent learning in mice in a water finding task.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Enhancement of hippocampal LTP, reference memory and sensorimotor gating in mutant mice lacking a telencephalon-specific cell adhesion molecule.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Mis-sense mutation Val&rarr;Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Alzheimer's disease: a dysfunction of the amyloid precursor protein(1).

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Age-related changes in learning and memory and cholinergic neuronal function in senescence accelerated mice (SAM).

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Age-related defects in lifespan and learning ability in SAMP8 mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence.

1 reference

https://api.crossref.org/works/10.1111%2FJ.0953-816X.2004.03397.X

21 January 2018

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

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21 January 2018

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

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21 January 2018

The fluorescent Congo red derivative, (trans, trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (BSB), labels diverse beta-pleated sheet structures in postmortem human neurodegenerative disease brains

1 reference

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21 January 2018

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

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21 January 2018

Visual identification and spatial location in Alzheimer's disease.

1 reference

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21 January 2018

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

1 reference

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21 January 2018

A novel ES cell line, TT2, with high germline-differentiating potency

1 reference

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21 January 2018

Genomic organization of the human amyloid beta-protein precursor gene

1 reference

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21 January 2018

Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val→Ile mutation in the amyloid precursor protein gene

1 reference

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21 January 2018

Identifiers

10.1111/J.0953-816X.2004.03397.X

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15147316%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15147316%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

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