(Q44934620)

7 December 2017

title

Critical role of transmembrane segment zinc binding in the structure and function of rhodopsin (English)

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7 December 2017

main subject

transmembrane protein

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2

Jeremiah Stitham

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7 December 2017

author name string

Aleksandar Stojanovic

series ordinal

1

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7 December 2017

John Hwa

series ordinal

3

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7 December 2017

language of work or name

English

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publication date

12 June 2004

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Journal of Biological Chemistry

7 December 2017

published in

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7 December 2017

volume

279

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7 December 2017

issue

34

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7 December 2017

page(s)

35932-35941

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Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126.

7 December 2017

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Rhodopsin and retinitis pigmentosa: shedding light on structure and function

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Zinc-induced decrease of the thermal stability and regeneration of rhodopsin.

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Identification of an allosteric binding site for Zn2+ on the beta2 adrenergic receptor

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Metal ion enhanced binding of AMD3100 to Asp262 in the CXCR4 receptor

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Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

21 January 2018

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21 January 2018

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Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography.

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Retinitis pigmentosa rhodopsin mutations L125R and A164V perturb critical interhelical interactions: new insights through compensatory mutations and crystal structure analysis

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Mechanism of rhodopsin activation as examined with ring-constrained retinal analogs and the crystal structure of the ground state protein

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The C9 methyl group of retinal interacts with glycine-121 in rhodopsin.

21 January 2018

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Role of the C9 methyl group in rhodopsin activation: characterization of mutant opsins with the artificial chromophore 11-cis-9-demethylretinal.

21 January 2018

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Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant.

21 January 2018

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21 January 2018

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Catalysis by metal-activated hydroxide in zinc and manganese metalloenzymes

21 January 2018

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TAUTOMERIC FORMS OF METARHODOPSIN.

21 January 2018

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21 January 2018

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Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled

21 January 2018

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Structure and function in rhodopsin: Mass spectrometric identification of the abnormal intradiscal disulfide bond in misfolded retinitis pigmentosa mutants

21 January 2018

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Structure and function in rhodopsin: further elucidation of the role of the intradiscal cysteines, Cys-110, -185, and -187, in rhodopsin folding and function

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M403821200

1 reference

7 December 2017

1 reference