(Q44976819)

English

The induction of cytochrome P450 3A5 (CYP3A5) in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated receptor (CAR).

scientific article published on 12 July 2004

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

The induction of cytochrome P450 3A5 (CYP3A5) in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated receptor (CAR). (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Ulrich M. Zanger

7

object named as

Ulrich M Zanger

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

author name string

Oliver Burk

1

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Ina Koch

2

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Judy Raucy

3

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Elisabeth Hustert

4

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Michel Eichelbaum

5

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Jürgen Brockmöller

6

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Leszek Wojnowski

8

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

language of work or name

0 references

publication date

12 July 2004

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

37

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

38379-38385

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Substrates of human hepatic cytochrome P450 3A4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Pharmacogenomics: translating functional genomics into rational therapeutics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Pharmacokinetic drug interactions with antimicrobial agents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Clinically significant drug interactions with antituberculosis agents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Sequence of the 5'-flanking region of CYP3A5: comparative analysis with CYP3A4 and CYP3A7

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Regulation of CYP3A5 by glucocorticoids and cigarette smoke in human lung-derived cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Expression and cyclic variability of CYP3A4 and CYP3A7 isoforms in human endometrium and cervix during the menstrual cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Sex is a major determinant of CYP3A4 expression in human liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Cytochrome P450 3A and their regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Functionally conserved xenobiotic responsive enhancer in cytochrome P450 3A7.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Pharmacokinetics of midazolam and 1'-hydroxymidazolam in Chinese with different CYP3A5 genotypes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Quantitative RT-PCR Measurement of Human Cytochrome P-450s: Application to Drug Induction Studies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404949200

21 January 2018

Identifiers

10.1074/JBC.M404949200

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44976819&oldid=1227971918"