(Q45029733)

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Modulation of effector cell functions in experimental autoimmune encephalomyelitis by leflunomide--mechanisms independent of pyrimidine depletion

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 December 2017

Modulation of effector cell functions in experimental autoimmune encephalomyelitis by leflunomide--mechanisms independent of pyrimidine depletion (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

experimental autoimmune encephalomyelitis

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1

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

Klaus Viktor Toyka

3

object named as

Klaus Toyka

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Europe PubMed Central

PubMed publication ID

8 December 2017

author name string

Tim Magnus

2

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Europe PubMed Central

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8 December 2017

Stefan Jung

4

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Europe PubMed Central

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8 December 2017

publication date

24 August 2004

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Europe PubMed Central

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8 December 2017

Journal of Leukocyte Biology

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Europe PubMed Central

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8 December 2017

76

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Europe PubMed Central

PubMed publication ID

8 December 2017

5

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Europe PubMed Central

PubMed publication ID

8 December 2017

950-960

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Europe PubMed Central

PubMed publication ID

8 December 2017

Molecular mechanisms of action of new xenobiotic immunosuppressive drugs: tacrolimus (FK506), sirolimus (rapamycin), mycophenolate mofetil and leflunomide

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

A771726, the active metabolite of leflunomide, directly inhibits the activity of cyclo-oxygenase-2 in vitro and in vivo in a substrate-sensitive manner

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Dihydroorotate dehydrogenase is a high affinity binding protein for A77 1726 and mediator of a range of biological effects of the immunomodulatory compound

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Leflunomide: an immunomodulatory drug for the treatment of rheumatoid arthritis and other autoimmune diseases

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Restriction of de novo pyrimidine biosynthesis inhibits Th1 cell activation and promotes Th2 cell differentiation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Leflunomide inhibits activation of inducible nitric oxide synthase in rat astrocytes

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double-blind, randomised, multicentre trial. European Leflunomide Study Group.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

The use of leflunomide in the treatment of rheumatoid arthritis: an experimental and clinical review

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Suppression of experimental autoimmune neuritis by leflunomide

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Effects of leflunomide on immune responses and models of inflammation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

T cell vaccination does not induce resistance to experimental autoimmune neuritis

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

The role of macrophages and eicosanoids in the pathogenesis of experimental allergic neuritis. Serial clinical, electrophysiological, biochemical and morphological observations

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Production of nitrite by neonatal rat microglial cells/brain macrophages

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Reversibility of T helper 1 and 2 populations is lost after long-term stimulation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

T cell aggregation induced through CD43: intracellular signals and inhibition by the immunomodulatory drug leflunomide.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Anti-CD43 inhibition of T cell homing

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Leflunomide-mediated suppression of antiviral antibody and Tcell responses: differential restoration by uridine

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Microglia induce CD4 T lymphocyte final effector function and death

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Microglial phagocytosis of apoptotic inflammatory T cells leads to down-regulation of microglial immune activation.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504308

21 January 2018

Identifiers

10.1189/JLB.0504308

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

ResearchGate publication ID

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