(Q45041939)

English

Inhibition of phosphatidylinositol-3-kinase enhances insulin stimulation of insulin receptor substrate 1 tyrosine phosphorylation and extracellular signal-regulated kinases in mouse R- fibroblasts

scientific article published in February 2004

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scholarly article

1 reference

Europe PubMed Central

8 December 2017

Inhibition of phosphatidylinositol-3-kinase enhances insulin stimulation of insulin receptor substrate 1 tyrosine phosphorylation and extracellular signal-regulated kinases in mouse R- fibroblasts (English)

1 reference

Europe PubMed Central

8 December 2017

phosphorylation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Woo S Choi

1

1 reference

Europe PubMed Central

8 December 2017

Chin K Sung

2

1 reference

Europe PubMed Central

8 December 2017

publication date

1 February 2004

1 reference

Europe PubMed Central

8 December 2017

Journal of Receptors and Signal Transduction

1 reference

Europe PubMed Central

8 December 2017

24

1 reference

Europe PubMed Central

8 December 2017

67-83

1 reference

Europe PubMed Central

8 December 2017

1-2

1 reference

Europe PubMed Central

8 December 2017

Insulin signalling and the regulation of glucose and lipid metabolism

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

PI3K: downstream AKTion blocks apoptosis

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

The IRS-signalling system: a network of docking proteins that mediate insulin action

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Regulation of the Akt/Glycogen synthase kinase-3 axis by insulin-like growth factor-II via activation of the human insulin receptor isoform-A

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Nonradioactive determination of Ras-GTP levels using activated ras interaction assay

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

How receptor tyrosine kinases activate Ras.

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

The insulin signalling system and the IRS proteins

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphory

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Differential regulation of insulin-stimulated tyrosine phosphorylation of IRS-1 and SHC by Wortmannin in intact cells

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin.

1 reference

https://api.crossref.org/works/10.1081%2FRRS-120034229

21 January 2018

Identifiers

10.1081/RRS-120034229

1 reference

Europe PubMed Central

8 December 2017

1 reference

Europe PubMed Central

8 December 2017

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