(Q45053321)

English

In situ transport of vinblastine and selected P-glycoprotein substrates: implications for drug-drug interactions at the mouse blood-brain barrier

scientific article published in August 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

In situ transport of vinblastine and selected P-glycoprotein substrates: implications for drug-drug interactions at the mouse blood-brain barrier (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

blood–brain barrier

1 reference

based on heuristic

drug interaction

0 references

1 reference

based on heuristic

Salvatore Cisternino

1

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Jean-Michel Scherrmann

4

object named as

Jean-Michel Scherrmann

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

author name string

Christophe Rousselle

2

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Marcel Debray

3

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

publication date

1 August 2004

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

21

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

1382-1389

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Multidrug resistance-reversing agents increase vinblastine distribution in normal tissues expressing the P-glycoprotein but do not enhance drug penetration in brain and testis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity relationship of P-glycoprotein substrates and modifiers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative structure-activity relationship of multidrug resistance reversal agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tracer kinetic model of blood-brain barrier transport of plasma protein-bound ligands. Empiric testing of the free hormone hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of steroids and verapamil on P-glycoprotein ATPase activity: progesterone, desoxycorticosterone, corticosterone and verapamil are mutually non-exclusive modulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of the multidrug transporter (P-glycoprotein) and its reversal

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacokinetics of vinblastine after a 96-hour continuous infusion in wild-type mice and mice lacking mdr1a P-glycoprotein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphine blood-brain barrier transport is influenced by probenecid co-administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein substrates and antagonists cluster into two distinct groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-dependent brain penetration of SDZ PSC 833, a novel multidrug resistance-reversing cyclosporin, in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperativity in the inhibition of P-glycoprotein-mediated daunorubicin transport: evidence for half-of-the-sites reactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive and non-competitive inhibition of the multidrug-resistance-associated P-glycoprotein ATPase--further experimental evidence for a multisite model

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of modulators of the multidrug resistance pump on the distribution of vinblastine in tissues of the mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonlinear accumulation in the brain of the new taxoid TXD258 following saturation of P-glycoprotein at the blood-brain barrier in mice and rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic parameters for reversal of the multidrug pump as measured for drug accumulation and cell killing

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug-protein binding and blood-brain barrier permeability.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new multidrug resistance protein at the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An in situ brain perfusion technique to study cerebrovascular transport in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening of multidrug-resistance sensitive drugs by in situ brain perfusion in P-glycoprotein-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug efflux transporters in the CNS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic profiling of P-glycoprotein-mediated drug efflux in rat and human intestinal epithelia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo saturation of the transport of vinblastine and colchicine by P-glycoprotein at the rat blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linear and cyclic peptides as substrates and modulators of P-glycoprotein: peptide binding and effects on drug transport and accumulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine [seecomments]

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of two pharmacophores on the multidrug transporter P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic and natural opiates interact with P-glycoprotein in multidrug-resistant cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation between the turnover number for vinblastine transport and for vinblastine-stimulated ATP hydrolysis by human P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of lipoproteins in the plasma binding of SDZ PSC 833, a novel multidrug resistance-reversing cyclosporin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of an in situ mouse brain perfusion model and its application to mdr1a P-glycoprotein-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoids: binding affinity and lipophilicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Communication between multiple drug binding sites on P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/B:PHAM.0000036911.49191.DA

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

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