(Q45065966)

9 December 2017

title

Inhibitory effects of memantine on human cytochrome P450 activities: prediction of in vivo drug interactions (English)

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9 December 2017

3

Eva Anzenbacherova

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9 December 2017

4

Pavel Anzenbacher

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9 December 2017

Stanislav Micuda

1

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9 December 2017

Lucie Mundlova

2

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9 December 2017

Jaroslav Chladek

5

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9 December 2017

Leos Fuksa

6

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9 December 2017

Jirina Martinkova

7

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9 December 2017

publication date

16 September 2004

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European Journal of Clinical Pharmacology

9 December 2017

published in

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9 December 2017

volume

60

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9 December 2017

issue

8

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9 December 2017

page(s)

583-589

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Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro.

9 December 2017

cites work

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12 December 2020

The role of CYP2B6 in human xenobiotic metabolism

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12 December 2020

Characteristics of a microsomal cytochrome P-448-mediated reaction. Ethoxyresorufin O-de-ethylation

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12 December 2020

Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1

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12 December 2020

The determination of enzyme inhibitor constants

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12 December 2020

A simple graphical method for determining the inhibition constants of mixed, uncompetitive and non-competitive inhibitors

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12 December 2020

Species differences in the covalent binding of [14C]tamoxifen to liver microsomes and the forms of cytochrome P450 involved

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12 December 2020

High-performance liquid chromatography determination of dextromethorphan and dextrorphan for oxidation phenotyping by fluorescence and ultraviolet detection

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12 December 2020

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

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12 December 2020

Electrophysiological study, biodistribution in mice, and preliminary PET evaluation in a rhesus monkey of 1-amino-3-[18F]fluoromethyl-5-methyl-adamantane (18F-MEM): a potential radioligand for mapping the NMDA-receptor complex

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12 December 2020

Evaluation of the selectivity of In vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities

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12 December 2020

Non-cholinergic strategies for treating and preventing Alzheimer's disease

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12 December 2020

Human cytochrome P4502B6: interindividual hepatic expression, substrate specificity, and role in procarcinogen activation

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12 December 2020

Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism

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12 December 2020

High-performance liquid chromatographic determination of chlorzoxazone and 6-hydroxychlorzoxazone in serum: a tool for indirect evaluation of cytochrome P4502E1 activity in humans

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12 December 2020

Human CYP2B6: expression, inducibility and catalytic activities

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12 December 2020

The mechanism-based inactivation of human cytochrome P450 2B6 by phencyclidine

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12 December 2020

Influence of urine pH and urinary flow on the renal excretion of memantine

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12 December 2020

Evaluation of possible pro- or antioxidative properties and of the interaction capacity with the microsomal cytochrome P450 system of different NMDA-receptor ligands and of taurine in vitro

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12 December 2020

Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin

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12 December 2020

Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes

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12 December 2020

Potential and current use of N-methyl-D-aspartate (NMDA) receptor antagonists in diseases of aging

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12 December 2020

The effects of memantine on the subjective, reinforcing and cardiovascular effects of cocaine in humans.

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12 December 2020

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12 December 2020

A simple and sensitive assay of 7-ethoxycoumarin deethylation

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12 December 2020

Evidence supporting the interaction of CYP2B4 and CYP1A2 in microsomal preparations

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12 December 2020

Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes

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12 December 2020

Mechanism-based inactivation of cytochrome P450 2B6 by a novel terminal acetylene inhibitor

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12 December 2020

Identification of tamoxifen-DNA adducts in the endometrium of women treated with tamoxifen.

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12 December 2020

Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene

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12 December 2020

Assessment of drug-drug interactions: concepts and approaches

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12 December 2020

Investigation on possible antioxidative properties of the NMDA-receptor antagonists ketamine, memantine, and amantadine in comparison to nicanartine in vitro.

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12 December 2020

Pharmacodynamics and pharmacokinetics of memantine

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12 December 2020

Extrapolating in vitro data on drug metabolism to in vivo pharmacokinetics: evaluation of the pharmacokinetic interaction between amitriptyline and fluoxetine.

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12 December 2020

Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation

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12 December 2020

Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily.

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12 December 2020

Depression of hepatic microsomal enzyme systems by amantadine hydrochloride in the rat

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12 December 2020

Relationships between inhibition constants, inhibitor concentrations for 50% inhibition and types of inhibition: new ways of analysing data

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12 December 2020

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism

1 reference

12 December 2020

Hepatic metabolism of tolbutamide: characterization of the form of cytochrome P-450 involved in methyl hydroxylation and relationship to in vivo disposition

1 reference

12 December 2020

Amantadine and memantine are NMDA receptor antagonists with neuroprotective properties.

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12 December 2020

Characterization of cytochrome P-450 2B6 in human liver microsomes.

1 reference

12 December 2020

New selective inhibitors of cytochromes P450 2B and their application to antimutagenesis of tamoxifen.

1 reference

12 December 2020

Ritonavir, efavirenz, and nelfinavir inhibit CYP2B6 activity in vitro: potential drug interactions with bupropion

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12 December 2020

10.1007/S00228-004-0825-1

Identifiers

DOI

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Dimensions Publication ID

9 December 2017

1037164966

0 references

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