(Q30577448)

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Extrapolating in vitro data on drug metabolism to in vivo pharmacokinetics: evaluation of the pharmacokinetic interaction between amitriptyline and fluoxetine.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10335452%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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Europe PubMed Central

Extrapolating in vitro data on drug metabolism to in vivo pharmacokinetics: evaluation of the pharmacokinetic interaction between amitriptyline and fluoxetine (English)

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10335452%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

pharmacokinetics

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Richard I. Shader

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10335452%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Jerold S. Harmatz

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J S Harmatz

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10335452%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

David J. Greenblatt

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D J Greenblatt

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10335452%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Lisa L. von Moltke

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L L von Moltke

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10335452%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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J Schmider

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8 December 2019

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1 May 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10335452%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Drug Metabolism Reviews

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10335452%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

31

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8 December 2019

2

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8 December 2019

545-560

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8 December 2019

Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Relationship of in vitro data on drug metabolism to in vivo pharmacokinetics and drug interactions: implications for diazepam disposition in humans.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Enzyme kinetic modelling as a tool to analyse the behaviour of cytochrome P450 catalysed reactions: application to amitriptyline N-demethylation

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Inhibition of cytochrome P450 by nefazodone in vitro: studies of dextromethorphan O- and N-demethylation

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Inhibition of CYP2C9 by selective serotonin reuptake inhibitors in vitro: studies of phenytoin p-hydroxylation

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Binding of drugs to tissues

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Methods of determining plasma and tissue binding of drugs. Pharmacokinetic consequences

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Prediction of drug distribution in vivo on the basis of in vitro binding data

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Inhibition of human cytochrome P450-3A isoforms by fluoxetine and norfluoxetine: in vitro and in vivo studies

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Tricyclic antidepressant plasma levels after fluoxetine addition.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Cytochromes P450 mediating the N-demethylation of amitriptyline

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Clinical pharmacokinetics of selective serotonin reuptake inhibitors

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Inhibition by fluoxetine of cytochrome P450 2D6 activity.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

In vitro prediction of the terfenadine-ketoconazole pharmacokinetic interaction.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

In vitro approaches to predicting drug interactions in vivo.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Metabolism of drugs by cytochrome P450 3A isoforms. Implications for drug interactions in psychopharmacology.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Biotransformation of mestranol to ethinyl estradiol in vitro: the role of cytochrome P-450 2C9 and metabolic inhibitors

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Characterization of six in vitro reactions mediated by human cytochrome P450: application to the testing of cytochrome P450-directed antibodies

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Phenacetin O-deethylation by human liver microsomes in vitro: inhibition by chemical probes, SSRI antidepressants, nefazodone and venlafaxine

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Human cytochromes mediating N-demethylation of fluoxetine in vitro

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Interpretation of blood and tissue concentrations in fatal self-ingested overdose involving amitriptyline: an update (1978-1979)

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Distribution of trimipramine and its major metabolites in a fatal overdose case

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Distribution of sertraline in postmortem cases

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

The Determination of the Triazolobenzodiazepine Triazolam in Post Modem Samples

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Extremely long plasma half-life of amitriptyline in a woman with the cytochrome P450IID6 29/29-kilobase wild-type allele--a slowly reversible interaction with fluoxetine

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Interindividual differences in amitriptyline demethylation

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Five distinct human cytochromes mediate amitriptyline N-demethylation in vitro: dominance of CYP 2C19 and 3A4

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Metabolism of the Tricyclic Antidepressant Amitriptyline by cDNA-Expressed Human Cytochrome P450 Enzymes

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Enantioselective amitriptyline metabolism in patients phenotyped for two cytochrome P450 isozymes

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Steady-state kinetics of fluoxetine and amitriptyline in patients treated with a combination of these drugs as compared with those treated with amitriptyline alone

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: relation to pharmacokinetic interactions in vivo

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101935

21 January 2018

Identifiers

10.1081/DMR-100101935

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10335452%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10335452%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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