(Q45081451)

9 December 2017

Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs (English)

1 reference

9 December 2017

7

Joseph L Goldstein

1 reference

9 December 2017

Christopher M Adams

1

1 reference

9 December 2017

Julian Reitz

2

1 reference

9 December 2017

Jef K De Brabander

3

1 reference

9 December 2017

Jamison D Feramisco

4

1 reference

9 December 2017

Lu Li

5

1 reference

9 December 2017

Michael S Brown

6

1 reference

9 December 2017

language of work or name

English

0 references

publication date

27 September 2004

1 reference

Journal of Biological Chemistry

9 December 2017

9

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

9 December 2017

279

1 reference

9 December 2017

52772-52780

1 reference

9 December 2017

50

1 reference

Biological activity of some oxygenated sterols

9 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Receptor-mediated uptake of low density lipoprotein reconstituted with 25-hydroxycholesteryl oleate suppresses 3-hydroxy-3-methylglutaryl-coenzyme A reductase and inhibits growth of human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

A receptor-mediated pathway for cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Cellular cholesterol efflux mediated by cyclodextrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Regulated cleavage of sterol regulatory element binding proteins requires sequences on both sides of the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Transport-Dependent Proteolysis of SREBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Three different rearrangements in a single intron truncate sterol regulatory element binding protein-2 and produce sterol-resistant phenotype in three cell lines. Role of introns in protein evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

The enzymes, regulation, and genetics of bile acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Behavior of a photoactivatable analog of cholesterol, 6-photocholesterol, in model membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Distribution and transport of cholesterol in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Oxysterol binding protein and its homologues: new regulatory factors involved in lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410302200

Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi

21 January 2018

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M410302200

Membrane topology of human insig-1, a protein regulator of lipid synthesis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M410302200

Steroid Requirements for Suppression of HMG CoA Reductase Activity in Cultured Human Fibroblasts

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M410302200

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M410302200

19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M410302200

Oxysterol binding protein

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M410302200

Identifiers

DOI

10.1074/JBC.M410302200

1 reference

9 December 2017

1 reference