(Q45091101)

9 December 2017

title

Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease (English)

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9 December 2017

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5

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9 December 2017

7

Gerd Multhaup

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9 December 2017

Carina Treiber

1

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9 December 2017

Andreas Simons

2

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9 December 2017

Markus Strauss

3

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9 December 2017

Mathias Hafner

4

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9 December 2017

Thomas A Bayer

6

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9 December 2017

language of work or name

English

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publication date

30 September 2004

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Journal of Biological Chemistry

9 December 2017

published in

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9 December 2017

volume

279

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9 December 2017

issue

50

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9 December 2017

page(s)

51958-51964

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Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

9 December 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M407410200

Evidence for a copper-binding superfamily of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

In vivo reduction of amyloid-beta by a mutant copper transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Elevation of serum copper levels in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Elemental imbalances in the olfactory pathway in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Expression of human amyloid precursor protein ectodomains in Pichia pastoris: analysis of culture conditions, purification, and characterization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Function, structure, and mechanism of intracellular copper trafficking proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Pipes and wiring: the regulation of copper uptake and distribution in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

The beta A4 amyloid precursor protein binding to copper.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Changes in uptake of vitamin B(12) and trace metals in brains of mice treated with clioquinol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Mechanisms of biosynthesis of mammalian copper/zinc superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407410200

21 January 2018

Identifiers

DOI

10.1074/JBC.M407410200

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9 December 2017

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