(Q45127893)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

review article

1 reference

title

Time for a change in the research paradigm for Alzheimer's disease: the value of a chaotic matrix modeling approach (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Carol Brayne

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Robert P Friedland

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

publication date

16 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

CNS Neuroscience & Therapeutics

15 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

254-262

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments

15 January 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2009.00117.X

Presenilin structure, function and role in Alzheimer disease.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2009.00117.X

Oxidative stress in Alzheimer's disease

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2009.00117.X

Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice

21 January 2018

1 reference

12 December 2020

Apo E genotypes and risk of dementia in Down syndrome.

1 reference

12 December 2020

Molecular genetics of Alzheimer disease

1 reference

12 December 2020

Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons

1 reference

12 December 2020

Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice

1 reference

12 December 2020

Copernicus revisited: amyloid beta in Alzheimer's disease

1 reference

12 December 2020

Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS).

1 reference

12 December 2020

Beta -amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised

1 reference

12 December 2020

Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease.

1 reference

12 December 2020

Control of cholesterol turnover in the mouse

1 reference

12 December 2020

Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.

1 reference

12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

12 December 2020

Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein

1 reference

12 December 2020

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

1 reference

12 December 2020

The amyloid hypothesis: let sleeping dogmas lie?

1 reference

12 December 2020

Capacitative calcium entry induces hippocampal long term potentiation in the absence of presenilin-1.

1 reference

12 December 2020

Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory

1 reference

12 December 2020

EEG coherence in Alzheimer's dementia.

1 reference

12 December 2020

Amyloid-β: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-β

1 reference

12 December 2020

Hippocampal nitric oxide upregulation precedes memory loss and A beta 1-40 accumulation after chronic brain hypoperfusion in rats.

1 reference

12 December 2020

Up-regulation of soluble amyloid precursor protein fragment secretion in the rat retina in vivo by metabotropic glutamate receptor stimulation

1 reference

12 December 2020

Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the 'Dr. Jekyll and Mr. Hyde concept' of Alzheimer's disease or the yin and yang of neuroplasticity

1 reference

12 December 2020

Intraneuronal amyloid-beta1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death

1 reference

12 December 2020

Abnormal fronto-parietal coupling of brain rhythms in mild Alzheimer's disease: a multicentric EEG study.

1 reference

12 December 2020

Genetic aspects of Alzheimer's disease.

1 reference

12 December 2020

Wnt-3a overcomes beta-amyloid toxicity in rat hippocampal neurons.

1 reference

12 December 2020

Beta-secretase BACE1 is differentially controlled through muscarinic acetylcholine receptor signaling

1 reference

12 December 2020

Apolipoprotein E modulates gamma-secretase cleavage of the amyloid precursor protein

1 reference

12 December 2020

Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice.

1 reference

12 December 2020

Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis

1 reference

12 December 2020

The role of inflammation in Alzheimer's disease

1 reference

12 December 2020

Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture

1 reference

12 December 2020

Interactions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease

1 reference

12 December 2020

Trolox and 17beta-estradiol protect against amyloid beta-peptide neurotoxicity by a mechanism that involves modulation of the Wnt signaling pathway

1 reference

12 December 2020

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

12 December 2020

Fractional Gaussian noise, functional MRI and Alzheimer's disease.

1 reference

12 December 2020

Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide

1 reference

12 December 2020

Regulation of NMDA receptor trafficking by amyloid-beta

1 reference

12 December 2020

Amyloid-beta peptide inhibits activation of the nitric oxide/cGMP/cAMP-responsive element-binding protein pathway during hippocampal synaptic plasticity.

1 reference

12 December 2020

Alzheimer's disease amyloid-beta peptide modulates apolipoprotein E isoform specific receptor binding.

1 reference

12 December 2020

Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target

1 reference

12 December 2020

Fronto-parietal coupling of brain rhythms in mild cognitive impairment: a multicentric EEG study

1 reference

12 December 2020

Amyloid beta: the alternate hypothesis

1 reference

12 December 2020

1 reference

12 December 2020

Effects of apoE on neuronal signaling and APP processing in rodent brain.

1 reference

12 December 2020

Role of amyloid precursor protein, amyloid-beta and gamma-secretase in cholesterol maintenance

1 reference

12 December 2020

Mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons

1 reference

12 December 2020

The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism

1 reference

12 December 2020

Presenilin diversifies its portfolio.

1 reference

12 December 2020

Calcium and neurodegeneration

1 reference

12 December 2020

Regulation of alpha- and beta-secretase activity by oxysterols: cerebrosterol stimulates processing of APP via the alpha-secretase pathway

1 reference

12 December 2020

Oxysterols, cholesterol homeostasis, and Alzheimer disease

1 reference

12 December 2020

The molecular link between beta- and gamma-secretase activity on the amyloid beta precursor protein

1 reference

12 December 2020

ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity.

1 reference

12 December 2020

Alzheimer's disease: cholesterol, membrane rafts, isoprenoids and statins

1 reference

12 December 2020

Deregulation of NMDA-receptor function and down-stream signaling in APP[V717I] transgenic mice.

1 reference

12 December 2020

Amyloid beta protein modulates glutamate-mediated neurotransmission in the rat basal forebrain: involvement of presynaptic neuronal nicotinic acetylcholine and metabotropic glutamate receptors.

1 reference

12 December 2020

Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein

1 reference

12 December 2020

Amyloid beta peptides and glutamatergic synaptic dysregulation

1 reference

12 December 2020

Presenilin-1 mutation impairs cholinergic modulation of synaptic plasticity and suppresses NMDA currents in hippocampus slices

1 reference

12 December 2020

Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases

1 reference

12 December 2020

Effects of beta-amyloid peptide on the density of M2 muscarinic acetylcholine receptor protein in the hippocampus of the rat: relationship with GABA-, calcium-binding protein and somatostatin-containing cells

1 reference

12 December 2020

Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe/PS1dE9 mouse model of Alzheimer's disease

1 reference

12 December 2020

Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons

1 reference

12 December 2020

Beta-amyloid peptide-induced modifications in alpha7 nicotinic acetylcholine receptor immunoreactivity in the hippocampus of the rat: relationship with GABAergic and calcium-binding proteins perikarya

1 reference

12 December 2020

Endogenous secreted amyloid precursor protein-alpha regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory

1 reference

12 December 2020

Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

1 reference

12 December 2020

Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis

1 reference

12 December 2020

Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations

1 reference

12 December 2020

Overexpression of wild-type human APP in mice causes cognitive deficits and pathological features unrelated to Abeta levels.

1 reference

12 December 2020

Nicotinic receptor agonists and antagonists increase sAPPalpha secretion and decrease Abeta levels in vitro

1 reference

12 December 2020

Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

1 reference

12 December 2020

NMDA receptor-dependent signaling pathways that underlie amyloid beta-protein disruption of LTP in the hippocampus

1 reference

12 December 2020

Nicotinic receptor-mediated neuroprotection in neurodegenerative disease models

1 reference

12 December 2020

Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis

1 reference

12 December 2020

Regulated secretion of beta-amyloid precursor protein in rat brain

1 reference

12 December 2020

Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner

1 reference

12 December 2020

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

12 December 2020

Research and Alzheimer's disease: an epidemiological perspective.

1 reference

12 December 2020

Alpha-secretase-derived product of beta-amyloid precursor protein is decreased by presenilin 1 mutations linked to familial Alzheimer's disease.

1 reference

12 December 2020

Secreted amyloid precursor protein alpha selectively suppresses N-methyl-D-aspartate currents in hippocampal neurons: involvement of cyclic GMP.

1 reference

12 December 2020

10.1111/J.1755-5949.2009.00117.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002628%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

20002628

1 reference