(Q45161041)

10 December 2017

Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants (English)

1 reference

10 December 2017

Rituparna Chakrabarti

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Ruth Geiss-Friedlander

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Ellen Reisinger

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

12

Henning Urlaub

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

13

Nils Brose

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Nicola Strenzke

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Hanan Al-Moyed

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Alexandra Müller

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Gerhard Hoch

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Tina Pangrsic

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Gulnara Yamanbaeva

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Christof Lenz

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Kuan-Ting Pan

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Elisabeth Auge

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Carolin Wichmann

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

English

0 references

publication date

11 October 2016

1 reference

10 December 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

2519-2535

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

2 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5283603/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Molecular determinants of the human α2C-adrenergic receptor temperature-sensitive intracellular traffic

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Uniquantal release through a dynamic fusion pore is a candidate mechanism of hair cell exocytosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

A new probe for super-resolution imaging of membranes elucidates trafficking pathways

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Evidence for genotype-phenotype correlation for OTOF mutations

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Frequency tuning in the behaving mouse: different bandwidths for discrimination and generalization

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Otoferlin couples to clathrin-mediated endocytosis in mature cochlear inner hair cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Loudness adaptation accompanying ribbon synapse and auditory nerve disorders

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Otoferlin: a multi-C2 domain protein essential for hearing

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Spike encoding of neurotransmitter release timing by spiral ganglion neurons of the cochlea.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Sharp Ca²⁺ nanodomains beneath the ribbon promote highly synchronous multivesicular release at hair cell synapses

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Modulation of α(2C) adrenergic receptor temperature-sensitive trafficking by HSP90

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Onset coding is degraded in auditory nerve fibers from mutant mice lacking synaptic ribbons

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Screening mutations of OTOF gene in Chinese patients with auditory neuropathy, including a familial case of temperature-sensitive auditory neuropathy

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Temperature-sensitive auditory neuropathy associated with an otoferlin mutation: Deafening fever!

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Behaviorally measured audiograms and gap detection thresholds in CBA/CaJ mice

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

OTOF mutations revealed by genetic analysis of hearing loss families including a potential temperature sensitive auditory neuropathy allele

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

The afferent synapse of cochlear hair cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Non-syndromic recessive auditory neuropathy is the result of mutations in the otoferlin (OTOF) gene

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Transmitter release at the hair cell ribbon synapse

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Kinetics of exocytosis and endocytosis at the cochlear inner hair cell afferent synapse of the mouse

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

A mutation in OTOF, encoding otoferlin, a FER-1-like protein, causes DFNB9, a nonsyndromic form of deafness

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Transient deafness due to temperature-sensitive auditory neuropathy

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Spike activity recorded from the organ of Corti

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multiquantal release, and sound encoding at the hair cell afferent synapse.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

A prevalent founder mutation and genotype-phenotype correlations of OTOF in Japanese patients with auditory neuropathy

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Novel OTOF mutations in Brazilian patients with auditory neuropathy.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Probing the mechanism of exocytosis at the hair cell ribbon synapse.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Temperature enhances exocytosis efficiency at the mouse inner hair cell ribbon synapse.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Gap detection deficits in rats with tinnitus: a potential novel screening tool.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Hair cell synaptic ribbons are essential for synchronous auditory signalling.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Mutations in the OTOF gene in Taiwanese patients with auditory neuropathy

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27729456

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Calcium Dependence of Exocytosis and Endocytosis at the Cochlear Inner Hair Cell Afferent Synapse

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27729456

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.15252/EMBJ.201694564

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference