(Q45173708)

English

Structure and regulation of the murine reduced folate carrier gene: identification of four noncoding exons and promoters and regulation by dietary folates

scientific article published on 3 December 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 December 2017

Structure and regulation of the murine reduced folate carrier gene: identification of four noncoding exons and promoters and regulation by dietary folates (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

1 reference

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author name string

Mingjun Liu

1

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Yubin Ge

2

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Diane C Cabelof

3

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Amro Aboukameel

4

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Ahmad R Heydari

5

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Ramzi Mohammad

6

1 reference

Europe PubMed Central

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10 December 2017

Larry H Matherly

7

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

language of work or name

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publication date

3 December 2004

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Europe PubMed Central

PubMed publication ID

10 December 2017

number of pages

10

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

10 December 2017

280

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Europe PubMed Central

PubMed publication ID

10 December 2017

7

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Europe PubMed Central

PubMed publication ID

10 December 2017

5588-5597

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Folate receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Membrane transport of folates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Carrier-mediated membrane transport of folates in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

A prominent low-pH methotrexate transport activity in human solid tumors: contribution to the preservation of methotrexate pharmacologic activity in HeLa cells lacking the reduced folate carrier

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Molecular cloning of the human placental folate transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Organization, structure and alternate splicing of the murine RFC-1 gene encoding a folate transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Organization of the murine reduced folate carrier gene and identification of variant splice forms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Structural analysis of the human RFC-1 gene encoding a folate transporter reveals multiple promoters and alternatively spliced transcripts with 5' end heterogeneity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Structure and organization of the human reduced folate carrier gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Transcript heterogeneity of the human reduced folate carrier results from the use of multiple promoters and variable splicing of alternative upstream exons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Chromosomal localization of the murine RFC-1 gene encoding a folate transporter and its amplification in an antifolate resistant variant overproducing the transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Primary acute lymphoblastic leukemia cells use a novel promoter and 5'noncoding exon for the human reduced folate carrier that encodes a modified carrier translated from an upstream translational start

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Rescue of embryonic lethality in reduced folate carrier-deficient mice by maternal folic acid supplementation reveals early neonatal failure of hematopoietic organs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of the developing forebrain, hindbrain, neural tube, craniofacial region, eye, limb buds and heart

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Expression patterns of the multiple transcripts from the folylpolyglutamate synthetase gene in human leukemias and normal differentiated tissues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Intestinal folate transport: identification of a cDNA involved in folate transport and the functional expression and distribution of its mRNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Transcription of the mouse RFC-1 gene encoding a folate transporter. Multiplicity and properties of promoters with minimum requirements for their basal activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

The human reduced folate carrier gene is regulated by the AP2 and sp1 transcription factor families and a functional 61-base pair polymorphism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate carrier B promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Transcriptional regulation of the human reduced folate carrier promoter C: synergistic transactivation by Sp1 and C/EBP beta and identification of a downstream repressor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

The multidrug resistance protein family.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Folic acid: nutritional biochemistry, molecular biology, and role in disease processes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Folate-deficiency-induced homocysteinaemia in rats: disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

The half-life of the transcript encoding the folate receptor alpha in KB cells is reduced by cytosolic proteins expressed in folate-replete and not in folate-depleted cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Altered folate-binding protein mRNA stability in KB cells grown in folate-deficient medium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Aberrant methylation in the promoter region of the reduced folate carrier gene is a potential mechanism of resistance to methotrexate in primary central nervous system lymphomas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412662200

21 January 2018

Identifiers

10.1074/JBC.M412662200

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

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