(Q45224261)

11 December 2017

The mutation spectrum of purified AID is similar to the mutability index in Ramos cells and in ung(-/-)msh2(-/-) mice (English)

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11 December 2017

Mani Larijani

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11 December 2017

Darina Frieder

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2

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11 December 2017

Wajiha Basit

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3

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11 December 2017

Alberto Martin

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4

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11 December 2017

language of work or name

English

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publication date

14 January 2005

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11 December 2017

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11 December 2017

56

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11 December 2017

11

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11 December 2017

840-845

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https://scigraph.springernature.com/pub.10.1007/s00251-004-0748-0

11 December 2017

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cites work

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

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12 December 2020

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

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12 December 2020

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

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12 December 2020

Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process

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12 December 2020

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

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12 December 2020

DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine

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12 December 2020

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

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12 December 2020

Mismatch repair and immunoglobulin gene hypermutation: did we learn something?

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12 December 2020

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

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12 December 2020

The AID enzyme induces class switch recombination in fibroblasts

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12 December 2020

Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo

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12 December 2020

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

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12 December 2020

Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome

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12 December 2020

Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas

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12 December 2020

Methylation protects cytidines from AID-mediated deamination

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12 December 2020

Mechanism and control of class-switch recombination

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12 December 2020

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

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12 December 2020

Bcl-2 rescues the germinal center response but does not alter the V gene somatic hypermutation spectrum in MSH2-deficient mice.

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12 December 2020

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

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12 December 2020

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

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12 December 2020

Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line

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12 December 2020

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

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12 December 2020

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

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12 December 2020

AID mediates hypermutation by deaminating single stranded DNA.

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12 December 2020

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

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12 December 2020

AID and mismatch repair in antibody diversification

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12 December 2020

Activation-induced cytidine deaminase (AID) can target both DNA strands when the DNA is supercoiled

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12 December 2020

Severe attenuation of the B cell immune response in Msh2-deficient mice

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12 December 2020

Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination

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12 December 2020

Evolution of Ig DNA sequence to target specific base positions within codons for somatic hypermutation

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12 December 2020

Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice

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12 December 2020

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

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12 December 2020

Immunology. UNGstoppable switching

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12 December 2020

Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity

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12 December 2020

A novel cytidine deaminase AIDs in the delivery of error-prone polymerases to immunoglobulin genes

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12 December 2020

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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12 December 2020

Class-switch recombination: after the dawn of AID.

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12 December 2020

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

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12 December 2020

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

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12 December 2020

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin

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12 December 2020

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

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12 December 2020

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

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12 December 2020

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

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12 December 2020

10.1007/S00251-004-0748-0

Identifiers

DOI

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Dimensions Publication ID

11 December 2017

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