(Q45251261)

11 December 2017

Identification of the geometric requirements for allosteric communication between the alpha- and beta-subunits of tryptophan synthase (English)

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11 December 2017

2

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11 December 2017

3

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11 December 2017

Samanta Raboni

1

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language of work or name

English

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publication date

3 February 2005

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Journal of Biological Chemistry

11 December 2017

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11 December 2017

280

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11 December 2017

14

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11 December 2017

13450-13456

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Conformational change in substrate binding, catalysis and product release: an open and shut case?

11 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

The tryptophan synthase bienzyme complex transfers indole between the alpha- and beta-sites via a 25-30 A long tunnel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

The molecular basis of substrate channeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Loop closure and intersubunit communication in tryptophan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Allosteric communication in the tryptophan synthase bienzyme complex: roles of the beta-subunit aspartate 305-arginine 141 salt bridge

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Allosteric communication of tryptophan synthase. Functional and regulatory properties of the beta S178P mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

The molecular pathway for the allosteric regulation of tryptophan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Detection of open and closed conformations of tryptophan synthase by 15N-heteronuclear single-quantum coherence nuclear magnetic resonance of bound 1-15N-L-tryptophan

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Tryptophan synthase: a multienzyme complex with an intramolecular tunnel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Reciprocal communication between the lyase and synthase active sites of the tryptophan synthase bienzyme complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Structural basis for the impaired channeling and allosteric inter-subunit communication in the beta A169L/beta C170W mutant of tryptophan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Investigation of allosteric linkages in the regulation of tryptophan synthase: the roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Substitution of glutamic acid 109 by aspartic acid alters the substrate specificity and catalytic activity of the beta-subunit in the tryptophan synthase bienzyme complex from Salmonella typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Cryocrystallography and microspectrophotometry of a mutant (alpha D60N) tryptophan synthase alpha 2 beta 2 complex reveals allosteric roles of alpha Asp60

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Monovalent metal ions play an essential role in catalysis and intersubunit communication in the tryptophan synthase bienzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Conformational changes in the alpha-subunit coupled to binding of the beta 2-subunit of tryptophan synthase from Escherichia coli: crystal structure of the tryptophan synthase alpha-subunit alone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

PCR mutagenesis and overexpression of tryptophan synthase from Salmonella typhimurium: on the roles of beta2 subunit Lys-382.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

An active proteolytic derivative of the .alpha. subunit of tryptophan synthase. Identification of the site of cleavage and characterization of the fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

SERINE DEAMINATION BY THE B PROTEIN OF ESCHERICHIA COLI TRYPTOPHAN SYNTHETASE

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

The B protein of Escherichia coli tryptophan synthetase. II. New -elimination and -replacement reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Subunit communication in the tryptophan synthase alpha 2 beta 2 complex. Effects of beta subunit ligands on proteolytic cleavage of a flexible loop in the alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Tyrosine phenol-lyase and tryptophan indole-lyase encapsulated in wet nanoporous silica gels: Selective stabilization of tertiary conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Allosteric regulation of tryptophan synthase: effects of pH, temperature, and alpha-subunit ligands on the equilibrium distribution of pyridoxal 5'-phosphate-L-serine intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Monovalent cations affect dynamic and functional properties of the tryptophan synthase alpha 2 beta 2 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Regulation of tryptophan synthase by temperature, monovalent cations, and an allosteric ligand. Evidence from Arrhenius plots, absorption spectra, and primary kinetic isotope effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

Characterization of the functional role of a flexible loop in the alpha-subunit of tryptophan synthase from Salmonella typhimurium by rapid-scanning, stopped-flow spectroscopy and site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414521200

21 January 2018

Identifiers

DOI

10.1074/JBC.M414521200

1 reference

11 December 2017

1 reference

PubMed ID

15691828