(Q45264862)

11 December 2017

title

Switching pyridine nucleotide specificity in P450 BM3: mechanistic analysis of the W1046H and W1046A enzymes (English)

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11 December 2017

3

Nigel S Scrutton

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11 December 2017

Rajasekhar Neeli

1

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11 December 2017

Olivier Roitel

series ordinal

2

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11 December 2017

Andrew W Munro

series ordinal

4

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11 December 2017

language of work or name

English

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publication date

14 February 2005

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Journal of Biological Chemistry

11 December 2017

published in

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11 December 2017

volume

280

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11 December 2017

issue

18

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11 December 2017

page(s)

17634-17644

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P450BM-3 and other inducible bacterial P450 cytochromes: biochemistry and regulation

11 December 2017

cites work

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Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

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Redox control of the catalytic cycle of flavocytochrome P-450 BM3.

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Probing electron transfer in flavocytochrome P-450 BM3 and its component domains.

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The domain architecture of cytochrome P450BM-3.

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Determination of the redox properties of human NADPH-cytochrome P450 reductase

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Electron transfer in human cytochrome P450 reductase.

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Electron transfer in human methionine synthase reductase studied by stopped-flow spectrophotometry

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Cloning and characterization of a novel human dual flavin reductase

21 January 2018

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Mammalian nitric oxide synthases

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The crystal structure of the flavin containing enzyme dihydroorotate dehydrogenase A from Lactococcus lactis

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Nitric oxide synthase is a cytochrome P-450 type hemoprotein

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Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1

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Potentiometric analysis of the flavin cofactors of neuronal nitric oxide synthase

21 January 2018

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Molecular dissection of human methionine synthase reductase: determination of the flavin redox potentials in full-length enzyme and isolated flavin-binding domains

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Protein engineering of Bacillus megaterium CYP102. The oxidation of polycyclic aromatic hydrocarbons

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Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

21 January 2018

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Engineering of a functional human NADH-dependent cytochrome P450 system

21 January 2018

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Modification of the nucleotide cofactor-binding site of cytochrome P-450 reductase to enhance turnover with NADH in Vivo

21 January 2018

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A conserved flavin-shielding residue regulates NO synthase electron transfer and nicotinamide coenzyme specificity

21 January 2018

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Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase

21 January 2018

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Interaction of cytochrome c with flavocytochrome b2.

21 January 2018

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Thermodynamic and kinetic analysis of the isolated FAD domain of rat neuronal nitric oxide synthase altered in the region of the FAD shielding residue Phe1395.

21 January 2018

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A productive NADP+ binding mode of ferredoxin-NADP + reductase revealed by protein engineering and crystallographic studies

21 January 2018

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Crystal structure of oxidized flavodoxin, an essential protein in Helicobacter pylori

21 January 2018

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Interflavin electron transfer in human cytochrome P450 reductase is enhanced by coenzyme binding. Relaxation kinetic studies with coenzyme analogues

21 January 2018

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The FAD-shielding residue Phe1395 regulates neuronal nitric-oxide synthase catalysis by controlling NADP+ affinity and a conformational equilibrium within the flavoprotein domain

21 January 2018

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Regio- and enantioselective alkane hydroxylation with engineered cytochromes P450 BM-3.

21 January 2018

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P450 BM3: the very model of a modern flavocytochrome

21 January 2018

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Trp-676 Facilitates Nicotinamide Coenzyme Exchange in the Reductive Half-Reaction of Human Cytochrome P450 Reductase: Properties of the Soluble W676H and W676A Mutant Reductases†

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M413826200

1 reference

11 December 2017

1 reference